Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0UPV4

Entry ID Method Resolution Chain Position Source
AF-Q0UPV4-F1 Predicted AlphaFoldDB

No variants for Q0UPV4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0UPV4

No associated diseases with Q0UPV4

2 regional properties for Q0UPV4

Type Name Position InterPro Accession
domain NADPH-dependent FMN reductase-like 16 - 141 IPR005025
domain Flavodoxin/nitric oxide synthase 4 - 191 IPR008254

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chromatin The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
CMG complex A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.
GINS complex A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks.
replication fork protection complex A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
DNA unwinding involved in DNA replication The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
double-strand break repair via break-induced replication The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.
mitotic DNA replication initiation Any DNA replication initiation involved in mitotic cell cycle DNA replication.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSYYSVDAI LTDAQKVPCT FELTVPGLGF LEGNMSGDMK QGSKVELPLW LGEMLALSQS
70 80 90 100 110 120
LNTSSLVTLD PPSALSPRVL NALKADPRTV DLRALAPHFY DLGARILELF EEEKMIEVLS
130 140 150 160 170
DTFKARAAVI ADQAHNPRGA LGEGADFMRG LDENERQLFR AAHDSAKAAR TWMTDLKRK