Q0UEB6

PR
Gene name
SNOG_09898
Protein name
Mannitol 2-dehydrogenase
Names
M2DH, MDH
Species
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
KEGG Pathway
pno:SNOG_09898
EC number
1.1.1.67: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

18-123 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0UEB6

Entry ID Method Resolution Chain Position Source
AF-Q0UEB6-F1 Predicted AlphaFoldDB

No variants for Q0UEB6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0UEB6

No associated diseases with Q0UEB6

2 regional properties for Q0UEB6

Type Name Position InterPro Accession
domain Mannitol dehydrogenase, C-terminal 300 - 543 IPR013118
domain Mannitol dehydrogenase, N-terminal 107 - 271 IPR013131

Functions

Description
EC Number 1.1.1.67 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
mannitol 2-dehydrogenase activity Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.
mannitol dehydrogenase activity Catalysis of the reaction: D-mannitol + NAD(+) = D-mannose + H(+) + NADH.
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFSYLPRYPL RAASARALVR ATRPSYRSAL LRYQSSEAVG RTQEIVPGAY QIPPRDFSRQ
70 80 90 100 110 120
HEEKLAPKNA ARAPRRIEPA TLKLNSKNLS QLQNVTVPTY QREGVKQGIV HVGVGGFHRA
130 140 150 160 170 180
HLAAYVDTLL EQFNSQDWSI CGVDLQPFAA PMRDALGSQD NLYTMIECDT EGTSARVIGS
190 200 210 220 230 240
ITDYLFAPDN CEAVIAKMAH PDTHIVSMTV TESGYYMNEN THELQIDHPD IAADLAGQQP
250 260 270 280 290 300
PRTVFAYLYA ALARRHAAGL RPFTVMSCDN MQKNGDISRN MLLAFARQQN PEVADWIAEN
310 320 330 340 350 360
GAFPNSMVDR ITPRTSDENK AQLAQEFGVE DSWPVVTEVF HQWVLEDKFA DGRPPFEKAG
370 380 390 400 410 420
VQVVPNVHKV EEYELIKLRL LNASHSAMGY AGYLGGFTYI HEVIADPTFR KYIRNMMQEE
430 440 450 460 470 480
VQPLLPRIPG VSVDDYCNTL LGRFSNPTLK DELPRICLGG SGKIPQFIMP SIAEQIQAGG
490 500 510 520 530 540
PLRRLTLCAA AWFRYLRGIN EQGQAFKLDD PMAEELQAKA LESPFSVLEV KSLFGDDLRD
550 560
DKRFVAELKN ALESLERDGA RATIAQYA