Q0U6X2

PR
Gene name
MAK5 (SNOG_12492)
Protein name
ATP-dependent RNA helicase MAK5
Names
Species
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
KEGG Pathway
pno:SNOG_12492
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0U6X2

Entry ID Method Resolution Chain Position Source
AF-Q0U6X2-F1 Predicted AlphaFoldDB

No variants for Q0U6X2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0U6X2

No associated diseases with Q0U6X2

5 regional properties for Q0U6X2

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 409 - 417 IPR000629
domain Helicase, C-terminal 528 - 675 IPR001650
domain DEAD/DEAH box helicase domain 273 - 464 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 268 - 497 IPR014001
domain RNA helicase, DEAD-box type, Q motif 249 - 277 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKRAHKAPKA SHKAHKRQKV EKKPRPEINV PKRKIRLDDL GWNQVSMPDR LEDFEGFYGL
70 80 90 100 110 120
EEIEDVHVVK DAVTGNLSFE TTKTDEQIEQ DIEKAWQREE EEAKFLEKIT FGGEPKNGED
130 140 150 160 170 180
VVEEETAPVE DTVEATQDED AASWGGFSDD DVAQNGDEQS EDVQMVEEDA PPTPNVVLST
190 200 210 220 230 240
TKADGDGEAE PKKMNKRERA AEKKRIAALA KKTKKPDDDE ASEGKTFGPG AFDILANRAD
250 260 270 280 290 300
DEDDEVDVSA WEELELSTKI LESLAKLKFS KPTTIQASTI PEIMAGRDVI GKASTGSGKT
310 320 330 340 350 360
LAFGIPIIES YLASKSKSKD VKDKTPLALI IAPTRELAHQ ITAHLTALCA KGAFEAPLIA
370 380 390 400 410 420
SVTGGLAVQK QRRQLEKADI IVGTPGRLWE VISTGHGLLE KVKQIRFLVV DEADRLLSQG
430 440 450 460 470 480
NYKELGEILK ILEKDAPAEG EAEAEETTEV ERQTLVFSAT FQKGLQQKLA GKAKGGSDNL
490 500 510 520 530 540
MSKQQSMEYL LKKINFREEK PKFIDANPSS QMASKLKEGL IECAGTEKDL YLYSLLMFYP
550 560 570 580 590 600
KKRALIFTNS ISAVRRLTPF LQNLALPALP LHSSMAQKAR LRSIERFKER PGSILVATDV
610 620 630 640 650 660
AARGLDIPKV ELVIHYHLPR AADTYVHRSG RTARAEASGS SILICAPEEV GGVRRLIAKV
670 680 690 700 710 720
HARADEAPKS KKTAYFIRTL DIDRRIVARL KPRASISKKL ADTVIAKEKK HSEDDTLRQA
730 740 750 760 770 780
AEDLGVDYDS EEFEKEAKGK KGRGTGRKKK EKEASEMTKG EQQALRAELR GLLSQRINTG
790 800 810
VSARYLTSGG IDVDALMAGE GNMEFLGNVD GLGFDEE