Q0U3A4

PR
Gene name
SET9 (SNOG_13760)
Protein name
Histone-lysine N-methyltransferase SET9
Names
SET domain protein 9
Species
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
KEGG Pathway
pno:SNOG_13760
EC number
2.1.1.372: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

214-567 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0U3A4

Entry ID Method Resolution Chain Position Source
AF-Q0U3A4-F1 Predicted AlphaFoldDB

No variants for Q0U3A4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0U3A4

No associated diseases with Q0U3A4

1 regional properties for Q0U3A4

Type Name Position InterPro Accession
domain SET domain 114 - 234 IPR001214

Functions

Description
EC Number 2.1.1.372 Methyltransferases
Subcellular Localization
  • Nucleus
  • Chromosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
histone methyltransferase activity (H4-K20 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein.

2 GO annotations of biological process

Name Definition
chromatin organization The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.
histone H4-K20 trimethylation The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPPSKAEKRG LTLEKLASYD DVITDALVDK IYYWATIRKN RGTRFTASRG LQEEDIAGVI
70 80 90 100 110 120
REQVIWDKDP VEAVQQLLDL PGLRKYMKGL RDEKDQDQFK RHLRRYVNIY MPDCPFEVTT
130 140 150 160 170 180
TNRYTITDHE ASITARRDIN PREEIKYLTG VQVAMTEEQE KTLELARKDF SLVISSRKKT
190 200 210 220 230 240
RSLFLGPARF ANHDCDANAR LSTKGYDGMQ IVAVKPINEG DEITVSYGDD YFGDNNEECL
250 260 270 280 290 300
CHTCEDRQQN GWAPMKRVED SDDEDMEEAE SPVENPSEAT SSGTATSGGK RARDITEEDA
310 320 330 340 350 360
GADLPPTSKR ARIEKKPSPT KARASDHLRE ATLKKVHSTS SLRREMPVSS IEDPSANINV
370 380 390 400 410 420
TSPQMTQDIR NQQRDGLLTV SLDETSSSRE STPQSPLMAA SPKSSHSTDA TSVDDEHHVD
430 440 450 460 470 480
SLPKIKVEPE VVHENPALGV ATVKEEVITT TVNAPWPSPP AEDDEMSDLS ELSDSMEFDS
490 500 510 520 530 540
VKQQIVKRKF RPTLRTTRSK SRYEVHNRVG TPVSSAVGQD GEWVENPRKP GDYMTSSSLL
550 560 570 580 590 600
SAKFSKWVEC QTCDVQFVQQ DGYNTRKECP RCERHSKLYG YAWPKTEREG KHDKEERITD
610 620 630 640 650 660
HRIVHRFVDP DEERELKRGK TKKILKESIR ERFSTPRSGR ESMSASVEVD SGRKRRRVRK
TM