Q0SS02
Gene name |
xseA |
Protein name |
Exodeoxyribonuclease 7 large subunit |
Names |
Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit |
Species |
Clostridium perfringens (strain SM101 / Type A) |
KEGG Pathway |
cpr:CPR_1790 |
EC number |
3.1.11.6: Exodeoxyribonucleases producing 5'-phosphomonoesters |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0SS02
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0SS02-F1 | Predicted | AlphaFoldDB |
No variants for Q0SS02
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q0SS02 | |||||
No associated diseases with Q0SS02
4 regional properties for Q0SS02
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Aldo/keto reductase, conserved site | 47 - 64 | IPR018170-1 |
| conserved_site | Aldo/keto reductase, conserved site | 158 - 175 | IPR018170-2 |
| conserved_site | Aldo/keto reductase, conserved site | 276 - 291 | IPR018170-3 |
| domain | NADP-dependent oxidoreductase domain | 25 - 307 | IPR023210 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.11.6 | Exodeoxyribonucleases producing 5'-phosphomonoesters |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| exodeoxyribonuclease VII complex | An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| exodeoxyribonuclease VII activity | Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides. |
| nucleic acid binding | Binding to a nucleic acid. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA catabolic process | The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKLKTLSVGE | VNNYVKKLVE | NDFILKNLNV | KGEISNLKFH | SSGHIYFSLK | DENSKVNCIM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FKNNAVNLDF | RLEEGMKVEI | KARLGVYHKE | GTYQLYCENI | KKAGIGELFE | EFHKLKKELS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EEGIFDEKYK | RALPKFPKRI | GIITAKTGAA | VRDIINVIQR | RNKSLDIILY | PAKVQGENAA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DSIIEGIRYF | NNEKSVDVII | LGRGGGFIEE | LWAFNNRDLA | YEIFNSRIPT | VSAVGHEVDF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TISDFVSDMR | APTPSAAGEL | VSPSLQEMIN | DLLNKKEFLH | RAIDRKFLNA | KRDVDLLYKG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LKGNNPKDII | EKRIKEVNSL | EEKLNFLGKR | KIDKAKDELI | ALNSILQTLN | PLNTLGRGYS |
| 370 | 380 | 390 | |||
| VIMDKEDKVI | NNVSELKKND | MVKVIMKDGS | VNIDIKIINE |