Q0SRS1
Gene name |
dapH |
Protein name |
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase |
Names |
Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase |
Species |
Clostridium perfringens (strain SM101 / Type A) |
KEGG Pathway |
cpr:CPR_1876 |
EC number |
2.3.1.89: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0SRS1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0SRS1-F1 | Predicted | AlphaFoldDB |
No variants for Q0SRS1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q0SRS1 | |||||
No associated diseases with Q0SRS1
4 regional properties for Q0SRS1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Hexapeptide repeat | 105 - 119 | IPR001451-1 |
| repeat | Hexapeptide repeat | 166 - 199 | IPR001451-2 |
| domain | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal | 6 - 87 | IPR013710 |
| conserved_site | Hexapeptide transferase, conserved site | 175 - 203 | IPR018357 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.89 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tetrahydrodipicolinate N-acetyltransferase activity | Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| diaminopimelate biosynthetic process | The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls. |
| lysine biosynthetic process via diaminopimelate | The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSYNFTDPYE | IARFIKEVKK | STPVKVYLKG | NLEGVELGSI | ECYGNNDFYV | LFGESDEVAT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FLTENKDKIV | SFRLENDRRN | SAIPMLELLN | INARIEPGAI | IRDRVSIGDN | AVIMMGAVIN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IGAEIGESTM | VDMNAVIGAR | GKLGKRVHLG | AGAVVAGVLE | PPSKTPCIIE | DDVLIGANAV |
| 190 | 200 | 210 | 220 | 230 | |
| ILEGVKIGKG | SVVAAGSVVV | EDVPAGVVVA | GTPAKIIKSV | DEKTKDKTEI | LDDLRK |