Q0SR11

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Clostridium perfringens (strain SM101 / Type A)
KEGG Pathway
cpr:CPR_2139
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

763-834 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0SR11

Entry ID Method Resolution Chain Position Source
AF-Q0SR11-F1 Predicted AlphaFoldDB

No variants for Q0SR11

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0SR11

No associated diseases with Q0SR11

9 regional properties for Q0SR11

Type Name Position InterPro Accession
domain Helicase, C-terminal 419 - 643 IPR001650
conserved_site SEC-C motif 897 - 914 IPR004027
domain SecA DEAD-like, N-terminal 5 - 387 IPR011115
domain SecA Wing/Scaffold 616 - 826 IPR011116
domain SecA, preprotein cross-linking domain 227 - 343 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 88 - 246 IPR014001
domain SecA motor DEAD 2 - 617 IPR014018
conserved_site SecA conserved site 485 - 500 IPR020937
domain SecA, C-terminal helicase domain 405 - 587 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGLFDKIFGS YSDREVKRIT PIVDKIDSLG PEMEKLSDEE LKQKTFEFKD RYAKGESLDD
70 80 90 100 110 120
MLPEAFAVCR EASTRVLGMK HYREQLIGGI VLHQGRIAEM KTGEGKTLVA TLPVYLNAIA
130 140 150 160 170 180
GKGVHVITVN DYLATRDKEW MGQLYEFLGL TTGVIVHGLT NDQRREAYNA DITYGTNNEF
190 200 210 220 230 240
GFDYLRDNMV IYKEERVQRP LHYCIVDEVD SILIDEARTP LIISGAGSKS TDLYKIADFF
250 260 270 280 290 300
VKKLREEEDY TIDEKAHAAM LTDKGVAEAE KAFGIENYAD ANNMELQHHI TQALKANYVM
310 320 330 340 350 360
KRDKDYMVKD DEIAIVDEFT GRLMEGRRYS DGLHQAIEAK EGVKVQRESK TLATITFQNY
370 380 390 400 410 420
FRMYTKLAGM TGTALTEETE FREIYGLDVV VIPTHRPVQR QDHSDLVFKT AKGKYDAIVE
430 440 450 460 470 480
EIIETHKTGQ PVLVGTTSIE KSEYLSSLLK KKGVPHKVLN ARYHEQEAEI VSHAGELGNI
490 500 510 520 530 540
TIATNMAGRG TDIKLGEGVL EVGGLKIIGT ERHESRRIDN QLRGRSGRQG DKGHSRFYIS
550 560 570 580 590 600
LEDDLMRIFG SEKLQAVVDR LGLEETEAIE SKMVTKSIEN AQKKVEGNNF DIRKTLLGYD
610 620 630 640 650 660
DVMNKQREVI YKQRSQVLEG ENLEDSVQAM IEDVITNAVQ AHLGNIDEDD FEKELGDLIK
670 680 690 700 710 720
YLEDIMLPHG KFTVEELKTN SNEEITRKFI ECAREIYKEK EEFVGSEQMR EIERVIILRV
730 740 750 760 770 780
VDTKWMDHID DMDHLKQGIG LRAYKQQDPI QAYQMEGSAM FDEMINNIKI DTVRYLFHVK
790 800 810 820 830
VEAEKPQRER VAKETGASHG GDSQEIKKKP VKKEPKVGRN DLCPCGSGKK YKSCCGREVV