Q0P3R5

PR
Gene name
ubxn2b
Protein name
UBX domain-containing protein 2B
Names
NSFL1 cofactor p37, p97 cofactor p37
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:496062
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-301 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0P3R5

Entry ID Method Resolution Chain Position Source
AF-Q0P3R5-F1 Predicted AlphaFoldDB

No variants for Q0P3R5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0P3R5

No associated diseases with Q0P3R5

2 regional properties for Q0P3R5

Type Name Position InterPro Accession
domain UBX domain 267 - 349 IPR001012
domain SEP domain 157 - 251 IPR012989

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm, cytosol
  • Endoplasmic reticulum
  • Golgi apparatus
  • Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
  • Localizes to centrosome during mitotic prophase and metaphase
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
microtubule organizing center An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEERENSEEG DDGAGEEEEE DQGSGEDGGE VGAEREQEAE LKDSLRPSVL DLQLALARLC
70 80 90 100 110 120
EDEYQDQPSK MPVLGLQIKD HQFERSFSGN GKVPSPGKIV NELFKEAKEH GAIPIDDTSK
130 140 150 160 170 180
SSGAFYRART FTGRGYKLGD SSKREFEYMQ GEDPFEQGQE IQILLKLWSN GFSLDDGELR
190 200 210 220 230 240
SYSDPINAEF LESVKKGEIP VELQRLVHGG QVNLDMEDHQ DQEYIKPRLK FKAFSGEGKK
250 260 270 280 290 300
LGSVTPEIIS TPSSPEEEHK RFLNAEVDLD EHVPTTKIQI RLADGTRLIQ RFNLSHRIMD
310 320 330 340
VRQFIIHARS DFAQCDFALL TTFPNVELTD ETQTLEEADI LNTVILQRLK