Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q0MQE8

Entry ID Method Resolution Chain Position Source
AF-Q0MQE8-F1 Predicted AlphaFoldDB

No variants for Q0MQE8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0MQE8

No associated diseases with Q0MQE8

2 regional properties for Q0MQE8

Type Name Position InterPro Accession
domain Complex 1 LYR protein domain 14 - 71 IPR008011
domain NDUFB9, LYR domain 12 - 88 IPR045292

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mitochondrial respiratory chain complex I A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
mitochondrial electron transport, NADH to ubiquinone The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation.
mitochondrial respiratory chain complex I assembly The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFLASGAYL THRQKVLRLY KRALRHLESW CVQRDKYRYF ACLMRARFEE HKNEKDMVRA
70 80 90 100 110 120
TQLLKEAEEE FWYRQHPQPY IFPDSPGGTS YERYDCYKVP EWCLDDWHPS EKAMYPDYFA
130 140 150 160 170
KREQWKKLQR ESWEREVKQL QEETPPGGPL TEALPPARKE GDLPPLWWYI VTRPRERPM