Q0IHQ9

PR
Gene name
pxylp1
Protein name
2-phosphoxylose phosphatase 1
Names
Acid phosphatase-like protein 2
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:780077
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

30-104 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0IHQ9

Entry ID Method Resolution Chain Position Source
AF-Q0IHQ9-F1 Predicted AlphaFoldDB

No variants for Q0IHQ9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0IHQ9

No associated diseases with Q0IHQ9

1 regional properties for Q0IHQ9

Type Name Position InterPro Accession
active_site Histidine acid phosphatase active site 111 - 125 IPR033379

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
phosphatase activity Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

4 GO annotations of biological process

Name Definition
chondroitin sulfate proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
dephosphorylation The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
glycosaminoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.
positive regulation of heparan sulfate proteoglycan biosynthetic process Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6DH46 pxylp1 2-phosphoxylose phosphatase 1 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MLLRNRFLLL LALAGLLAFL SLSLQFFSRW LPVSLQLKTE MQVFPEFPVR LIQVGQGREE
70 80 90 100 110 120
GLGAKNRKRI MPEPLTEPPA LNPLYEANLY CNTPGAKERS MEGHAPPNLK LLSVQVIIRH
130 140 150 160 170 180
GDRYPLYTIP KTKRPDIDCV LEPGRKPSHP HLTDFISHMS KGVDTQMDGT LGSLPRLPNH
190 200 210 220 230 240
ILCEMGELTQ TGVVQHLRNG QLLKEIYLKK HRLLTSAWTA KHLYFESTGK SRTLQSGLAL
250 260 270 280 290 300
LYSLLPNFDW KKINVKHQWS TIFCSNHCDC PMRNHYLEEE QRRQYNFRVK NSLLEKTYIN
310 320 330 340 350 360
MAKIVGIPTR QLRASNPIDS LLCNFCHNAT FPCTKNGCID LEHFKVIKTH QLEDEKERYE
370 380 390 400 410 420
KQLYFKYALM ATHPLLNQTA NRMLRIAEGK KDELFALYSA HDVTLSPILS ALGLREARFP
430 440 450 460 470 480
RFAARLVFEL WHDPEKANNH YVRVLYNGED VTFQTSFCRD QLRSSKRPLC PLKKFSTFVQ
490 500
KDMFSSLNST SYYDACHQRL F