Q0HPH4

PR
Gene name
add
Protein name
Adenosine deaminase
Names
Adenosine aminohydrolase
Species
Shewanella sp (strain MR-7)
KEGG Pathway
shm:Shewmr7_4004
EC number
3.5.4.4: In cyclic amidines
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

215-286 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0HPH4

Entry ID Method Resolution Chain Position Source
AF-Q0HPH4-F1 Predicted AlphaFoldDB

No variants for Q0HPH4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0HPH4

No associated diseases with Q0HPH4

2 regional properties for Q0HPH4

Type Name Position InterPro Accession
domain Adenosine deaminase domain 7 - 327 IPR001365
active_site Adenosine/AMP deaminase active site 274 - 280 IPR006650

Functions

Description
EC Number 3.5.4.4 In cyclic amidines
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
2'-deoxyadenosine deaminase activity Catalysis of the reaction: 2'-deoxyadenosine + H2O = deoxyinosine + NH3.
adenosine deaminase activity Catalysis of the reaction: adenosine + H2O = inosine + NH3.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
nucleotide metabolic process The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
purine ribonucleoside monophosphate biosynthetic process The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MINTSIPLVD LHRHLDGNVR VNTIWELGHQ HGIALPADSL ETLAPFVQIQ GKETSLVAFL
70 80 90 100 110 120
KKLDWMVAVL ADLDAVKRVA YENVADAALS GLDYAELRFS PYYMAMNHKL PIEGVVEAVI
130 140 150 160 170 180
DGVKAGLKDY QVKINLIGIM SRSFGQAACA QELEGLLAHK QHLVAMDLAG DELGFPGELF
190 200 210 220 230 240
NEHFKRVRDA GLAITAHAGE AAGSQSMWQA IQELGATRIG HGVNAIHDPK LMDYLAKHRI
250 260 270 280 290 300
GIESCPTSNL HTSTVSSYAE HPFRTFMDAG VLISLNTDDP GVSAIDIKHE YRIAKSELGL
310 320 330
SYAELAQVQR NGVEMAFLSE SERKALYAAK A