Q0HIL9

PR
Gene name
nadA
Protein name
Quinolinate synthase
Names
Species
Shewanella sp (strain MR-4)
KEGG Pathway
she:Shewmr4_2025
EC number
2.5.1.72: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0HIL9

Entry ID Method Resolution Chain Position Source
AF-Q0HIL9-F1 Predicted AlphaFoldDB

No variants for Q0HIL9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0HIL9

No associated diseases with Q0HIL9

No regional properties for Q0HIL9

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q0HIL9

Functions

Description
EC Number 2.5.1.72 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.
quinolinate synthetase A activity Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.

1 GO annotations of biological process

Name Definition
NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSPSPFAPTI ETIDYPFPPK PIPLSDAEKA DYKARIKQLL IEKDAVLVAH YYTDPEIQAL
70 80 90 100 110 120
AEETGGCVSD SLEMARFGRD HPAKTLIVAG VKFMGETAKI LSPEKTILMP TLEATCSLDL
130 140 150 160 170 180
GCPIDKFSAF CDAHPDHTVV VYANTSAAVK ARADWVVTSS IALEIVEHLD SEGKKIIWGP
190 200 210 220 230 240
DRHLGSYIAK QTGAEMLMWQ GDCIVHDEFK ANALRDLKRV YPDAAILVHP ESPASVVAMA
250 260 270 280 290 300
DAVGSTSQLI KAAQTMANER FIVATDRGIF YKMQQAAPGK TLIEAPTGGN GATCKSCAHC
310 320 330 340 350
PWMAMNGLKA IEASLSDSDK TTHEIFVDED LRVKALIPLT RMLDFAKTLN MKVKGNA