Q0CYP4

PR
Gene name
ATEG_01190
Protein name
Mannitol 2-dehydrogenase
Names
M2DH, MDH
Species
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
KEGG Pathway
EC number
1.1.1.67: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0CYP4

Entry ID Method Resolution Chain Position Source
AF-Q0CYP4-F1 Predicted AlphaFoldDB

No variants for Q0CYP4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0CYP4

No associated diseases with Q0CYP4

2 regional properties for Q0CYP4

Type Name Position InterPro Accession
domain Mannitol dehydrogenase, C-terminal 231 - 475 IPR013118
domain Mannitol dehydrogenase, N-terminal 36 - 201 IPR013131

Functions

Description
EC Number 1.1.1.67 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
mannitol 2-dehydrogenase activity Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPLKLNSRN LAQIFAAGKD RVKVPTYQRG SAVKEGIVHV GVGGFHRAHL AVYVDQLMQN
70 80 90 100 110 120
HGVNDYAICG VGLQPFDAAM RDALRSQDHL YTVIERSAKG SFAHVVGSIN SYLFAPDNRE
130 140 150 160 170 180
AVIAKMAHPD THIVSLTITE SGYYYNENTH ELQAEHPDIQ FDLDPANEKT PRTTFGFLYA
190 200 210 220 230 240
ALARRHQQGL RPFTVLSCDN MQKNGSITRH MLESFARLRN PELAKWIAEQ GAFPNAMVDR
250 260 270 280 290 300
ITPQTSPTDK KALAETIGIE DSWPVVTEPF MQWVLEDQFS DGRPPFEKAG AQVVKNVHDV
310 320 330 340 350 360
EQFEKHKLRL LNGSHSAIGY AGQMAGFEYV HEVMEHPLYN RFVWQMMQEE VKPLLPEIPG
370 380 390 400 410 420
VDIDEYCKTL MERFSNPTIM DQLPRICLNA SGKIPQFIMP SIAEAIWVTG PFRRLCFVAA
430 440 450 460 470 480
AWFRYLNGID DSGKTFNVDD PMREELQAKA RAGGTNPAEL LNVKSLFGDD LRSDKRFLQE
490 500
ITTAMEAIAR DGIMKTMPKY VD