Q0CKU1

PR
Gene name
grc3 (ATEG_05693)
Protein name
Polynucleotide 5'-hydroxyl-kinase grc3
Names
Species
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-111 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0CKU1

Entry ID Method Resolution Chain Position Source
AF-Q0CKU1-F1 Predicted AlphaFoldDB

No variants for Q0CKU1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0CKU1

No associated diseases with Q0CKU1

1 regional properties for Q0CKU1

Type Name Position InterPro Accession
domain Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain 326 - 528 IPR032319

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
polynucleotide 5'-hydroxyl-kinase activity Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKRKAEKQQS AAPVSAFAAR KARQQAQIAA TPEPVKPPSA VETTEEPPSK KARTSPEEDT
70 80 90 100 110 120
PSQSVSPADR VQTRRSSRRK AEPSEIEKTP RRKTKTTPAT PPEHLTDGTV GRESGIQTPV
130 140 150 160 170 180
EEVSEPEGND VPLDDADRYE SPADTPALVE AFPLSKTRLN KSNIVYSDEH TLCVRIKEKL
190 200 210 220 230 240
SLVVIGHYDV WVKRGVISLM GAKLHPSPRL YRVYAPSTHS LPVIKCVSGV DGAAEVEIKS
250 260 270 280 290 300
CHSGIYRLRD LSPLYQRIWN GSNTSADKLT LKNAEPHARR TFSVLYTSTD DSLKRHLRPL
310 320 330 340 350 360
HLEKQWSSAI KSLSQKGGKL RALICGPKGS GKSTFSRYLL NHLLSPAPQT EPSYCNTDGV
370 380 390 400 410 420
AFLDLDPGQP EFAPMGQIYL AHLRSPVFGP PFSHPSLEGS QDGTVIRAHH IGASSPKDDP
430 440 450 460 470 480
DHYVLAATDL MDRYRALLAS YPQCPLIINY PGWIFGLGLE VATWLVRSLG LSDVIYMSEK
490 500 510 520 530 540
GPAEVVEPLG QAAAAARIPL TTLPSQPTDF VSRSSAQLRS MQMQSYFHMT RPADVSTPLW
550 560 570 580 590 600
LDQPMSRTRP FKVHYAGPHQ GIRGIMVMGS QIHPDLLHEA LDGSLVGVVA VESPNAILGH
610 620 630 640 650 660
SEVPGLANGV MGKQPSPAEE GSEDAVMDEA TEMVPTAPLA SIDSGITRSP HEDLPYLFVG
670 680 690 700 710 720
AGSCNPLDPK ASHCLGLALV RSVNVAARQL ELVTPIAASR IRDALQQGYG IVLVRGQLDN
730 740 750 760 770 780
PNWALSEEYY AARAAEKRHR RFVDSSRKDK VDDGTDDSAH TSAILKDRIR RASHVPWMTV
790 800 810
IEDNSRRQRE AAQREKSLWK LRKKAYPGSE SEGDW