Q0CIQ3

PR
Gene name
rrp3
Protein name
ATP-dependent rRNA helicase rrp3
Names
Species
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
KEGG Pathway
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0CIQ3

Entry ID Method Resolution Chain Position Source
AF-Q0CIQ3-F1 Predicted AlphaFoldDB

No variants for Q0CIQ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0CIQ3

No associated diseases with Q0CIQ3

5 regional properties for Q0CIQ3

Type Name Position InterPro Accession
domain S1 domain 63 - 131 IPR003029
domain K Homology domain 138 - 202 IPR004087
domain K Homology domain, type 1 141 - 186 IPR004088
domain RNA-binding domain, S1 61 - 131 IPR022967
domain Exosome complex component, N-terminal domain 9 - 44 IPR025721

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
small-subunit processome A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKNSSRDSS PEEVSPDTET PSTTTAPKTF RELGVIDSLC EACEELGYTA PTPIQERCIP
70 80 90 100 110 120
IALEGRDLIG LAETGSGKTA AFVLPMLQAL MDKPQQFHSL ILAPTRELAQ QIAHTVEALG
130 140 150 160 170 180
ARISVRCTLL IGGMDMISQA IALGKKPHVI VATPGRLLDH LENTKGFSLR TLKYLVLDEA
190 200 210 220 230 240
DRLLDLDFGP ILDKLLRLLP KRKTYLFSAT MSSKVESLQR ASLSDPVRVS VSTKNQTASK
250 260 270 280 290 300
LLQSYLFIPH KFKDFYLVYL LNERAGQMGI IFTRTVHETQ RLSIMLRNLG FPAIPIHGQL
310 320 330 340 350 360
SQSARLASLN KFRARSRNLL IATDVAARGL DIPAVDYVLN YDLPQDSKTY IHRVGRTARA
370 380 390 400 410 420
GKSGIAFSFV TQYEVELWLR IEDALGKKVE EYKPEKDEVM IFAERVNDAQ RVAALTMRDM
430 440
QDKDNKGRGP RNRKRTRDDL DQDDG