Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0CCP0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0CCP0-F1 | Predicted | AlphaFoldDB |
No variants for Q0CCP0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q0CCP0 | |||||
No associated diseases with Q0CCP0
6 regional properties for Q0CCP0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 413 - 461 | IPR001680-1 |
| repeat | WD40 repeat | 639 - 684 | IPR001680-2 |
| repeat | WD40 repeat | 688 - 729 | IPR001680-3 |
| repeat | WD40 repeat | 741 - 784 | IPR001680-4 |
| domain | BOP1, N-terminal domain | 154 - 413 | IPR012953 |
| conserved_site | WD40 repeat, conserved site | 439 - 453 | IPR019775 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| PeBoW complex | A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| large ribosomal subunit rRNA binding | Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA. |
| ribonucleoprotein complex binding | Binding to a complex of RNA and protein. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVNASKVSKK | RKAVTRDVEE | EAGVFSGDEL | NAENLDGALS | DNANELSSDE | DDSEVELVDE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FSDEDDEDEE | ELDSDEIPSD | GEEPKKKSAS | TAVDGPQADD | ESSSEDEQPN | FRIEKDANGE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DRYIYDEINP | DDNSDYSDVD | ENANTIGNIP | LKFYDEYPHI | GYDINGKKIM | RPAKGEALDA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LLDSIEIPKG | WTGLTDPSTG | KPLELSQDEL | ELLRKVQMNE | IPEEGYDPYE | PLMEWFSNKQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EIMPLSAAPE | PKRRFVPSKH | EAKRVMKIVK | AIKEGRILPY | KPPTEEDEDK | DVINYDLWAD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EAERPDHPMH | VPAPKLPPPG | YEESYHPPPE | YLPDKKERKA | WEETDPEDRE | QEFLPNDFGS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRKVPGYENF | VKEKFERCLD | LYLAPRVRRS | KLNIDPESLL | PKLPSPEELK | PFPTTCATVF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RGHKGRVRTV | SVDPSGVWLA | TGGDDGTLRV | WELLTGRQLW | TVKLSDEDAV | NVVRWRPGKD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AVVLAAGVGD | DIFLAVPPIV | DPELEKASLE | LIDAGWGYAA | SRPPPTAAEE | NKKNTPPQWI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RPSAALADSG | VCAVIPLRYV | VKTLSWHRRG | DYFVTVCPGS | STPASVAISI | HTLSKHLTQF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| PFRKRIKGGG | PPQTAHFHPS | KPILFVANQR | TIRAYDLSRQ | LLVKIVQPGA | RWISSFDIHP |
| 670 | 680 | 690 | 700 | 710 | 720 |
| TSSTAAGGDN | IIVGSYDRRL | LWHDLELSQR | PYKTLRYHRK | AIRSVKFHPG | GRYPLFADAS |
| 730 | 740 | 750 | 760 | 770 | 780 |
| DDGSLQIFHG | SVTGDMLSNA | SIVPLKVLKG | HKITGELGVL | DVDWHPREAW | CVSAGADGTC |
| RLWM |