Q0C9E6

PR
Gene name
set9 (ATEG_09688)
Protein name
Histone-lysine N-methyltransferase set9
Names
SET domain protein 9
Species
Aspergillus terreus (strain NIH 2624 / FGSC A1156)
KEGG Pathway
EC number
2.1.1.372: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

232-513 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0C9E6

Entry ID Method Resolution Chain Position Source
AF-Q0C9E6-F1 Predicted AlphaFoldDB

No variants for Q0C9E6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0C9E6

No associated diseases with Q0C9E6

4 regional properties for Q0C9E6

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) 226 - 405 IPR002314
domain Aminoacyl-tRNA synthetase, class II 172 - 415 IPR006195
domain Serine-tRNA synthetase, type1, N-terminal 1 - 109 IPR015866
domain Serine-tRNA ligase catalytic core domain 121 - 422 IPR033729

Functions

Description
EC Number 2.1.1.372 Methyltransferases
Subcellular Localization
  • Nucleus
  • Chromosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chromosome A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
histone methyltransferase activity (H4-K20 specific) Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein.

2 GO annotations of biological process

Name Definition
chromatin organization The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA.
histone H4-K20 methylation The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPSKARSSP AVERRDRLTL AKLASYDDVA TDALVDRAYF WTNTRKNRTK YIPVRGIMDD
70 80 90 100 110 120
KVAEILLHHV IVAKDTVKAE RELLAISGIK KYMAKLPSDR EKEWFRRHLR KYIQMYLPDC
130 140 150 160 170 180
PFEVTTTNRY TITEHEAAIC ARKFIKQGQE IKYLSGTLVP MTREEEQDLD LKRKDFSIVM
190 200 210 220 230 240
SSRRKTPSFF LGPARFANHD CDANGRLVTR GSEGMQVVAT RDIEIGEEIT VSYGEDYFGI
250 260 270 280 290 300
DNCECLCLTC ERAVRNGWAP QVDSEASSTA STPALNDETK SAHGSTSPQK RKYAPDADSD
310 320 330 340 350 360
ASASPTPQKR RKFSRQYSKL RTEVSLSGDV TAIEPDPEQN TKIAVETTTD VPKDKPATNG
370 380 390 400 410 420
VTENESNARV SENQRATSDR EPSSPLGVDE SQNSSASTAP TSLFDVGIKL EESTEAFTQE
430 440 450 460 470 480
TLTTTKAGSV ADSHGDGDCR QLTAGIEQEA LSELSESLEL DDKSGTVVKR RKRRTRRQVV
490 500 510 520 530 540
PSVEDESHRV RVPGDYTKTS KLLAQSYDRW VECRTCKTWF LQHNSYLTRR ECPRCERHSM
550 560 570 580 590 600
LYGFQWPKTD KDGPLDDEER VMDHRTVHRF LYPEEEARIS RRDRGVSFGV TPTPELSEPR
610 620
TETEDSEACD ERRNTRASRR RTQSLRMTM