Q0C1R0

PR
Gene name
HNE_1625
Protein name
PKHD-type hydroxylase HNE_1625
Names
Species
Hyphomonas neptunium (strain ATCC 15444)
KEGG Pathway
hne:HNE_1625
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

2-87 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0C1R0

Entry ID Method Resolution Chain Position Source
AF-Q0C1R0-F1 Predicted AlphaFoldDB

No variants for Q0C1R0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0C1R0

No associated diseases with Q0C1R0

3 regional properties for Q0C1R0

Type Name Position InterPro Accession
domain Oxoglutarate/iron-dependent dioxygenase 77 - 175 IPR005123
domain Prolyl 4-hydroxylase, alpha subunit 1 - 174 IPR006620
domain Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain 84 - 173 IPR044862

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
2-oxoglutarate-dependent dioxygenase activity Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.
iron ion binding Binding to an iron (Fe) ion.
L-ascorbic acid binding Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIVIENILGQ DVLTEVAAAL RELRWEDGRN TAGATARRVK RNQQADLSSR TGSKVREVLL
70 80 90 100 110 120
EAVKRHPVVE AYARPLKFAP PLISCSGEGD AYGLHIDNPV MGKGDARLRT DLSFTLFLSP
130 140 150 160 170 180
PESYDGGELE IETVFKTESV KLPAGSMVIY PSTELHRVTP VTSGERFVFV GWIQSAIKDA
190 200 210 220
AQRAILFDVT NLKAGLARRF PPGSPELLTL AKTESNLIRM WSDI