Q0BPD5

PR
Gene name
msrA
Protein name
Peptide methionine sulfoxide reductase MsrA
Names
Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase
Species
Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
KEGG Pathway
gbe:GbCGDNIH1_2419
EC number
1.8.4.11: With a disulfide as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

56-136 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0BPD5

Entry ID Method Resolution Chain Position Source
AF-Q0BPD5-F1 Predicted AlphaFoldDB

No variants for Q0BPD5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0BPD5

No associated diseases with Q0BPD5

1 regional properties for Q0BPD5

Type Name Position InterPro Accession
domain Peptide methionine sulphoxide reductase MsrA domain 3 - 162 IPR002569

Functions

Description
EC Number 1.8.4.11 With a disulfide as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
L-methionine:thioredoxin-disulfide S-oxidoreductase activity Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin.
peptide-methionine (S)-S-oxide reductase activity Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MWMETAVIGG GCFWCVEAVL RELNGVASIR PGYAGGHTAN PTYKEVCTGT TFHAEVVEVT
70 80 90 100 110 120
FDPAILSYVD LLRIFLTIHD PTTPNRQGAD VGTQYRSVIM PASTEQENAA RGVLAEVEAA
130 140 150 160 170 180
QIWQAPLSTT IEPLQIFYPA EPEHVDYFAR HPEAAYCQAV IAPKVRAFRK HAADHVRANI
SPNHA