Q0BM96

PR
Gene name
miaB
Protein name
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase
Names
(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase
Species
Francisella tularensis subsp holarctica (strain OSU18)
KEGG Pathway
fth:FTH_0872
EC number
2.8.4.3: Transferring alkylthio groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

86-163 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0BM96

Entry ID Method Resolution Chain Position Source
AF-Q0BM96-F1 Predicted AlphaFoldDB

No variants for Q0BM96

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0BM96

No associated diseases with Q0BM96

No regional properties for Q0BM96

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q0BM96

Functions

Description
EC Number 2.8.4.3 Transferring alkylthio groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.
methylthiotransferase activity Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.

1 GO annotations of biological process

Name Definition
tRNA modification The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKEQKKVFIK TLGCQMNEYD SARMHEVLNE HFDTVKTDDY KDADIILINT CSIREKAQEK
70 80 90 100 110 120
VFHELGRWKG LKKTNEDLII GVGGCVASQE GENIIKRAPF VDLVFGPQTI HRLPEMIKQK
130 140 150 160 170 180
QKSQQSQVDI SFPEVEKFDY LPEPKAEGAK AYVSIMEGCD KYCSYCVVPY TRGPEVNRPF
190 200 210 220 230 240
EDVLAECAIL AEQGVKEITL LGQNVNHYLG PMENGQTADL ALLIHFIAEI DGIERIRFTT
250 260 270 280 290 300
SHPVEFSQNL IDAYATVPEL ANHLHLPVQH GSDRILINMK RNHTILEFKQ KIRKLRAIRP
310 320 330 340 350 360
DITISSDFIV GFPGETEEDF QKLLDLVKEI NFDQSFSFIY SKRPGTPAAD LPDDTPMEVK
370 380 390 400 410 420
KDRLKRLQDL LNSNAQIISR QMVGTNQRIL VDGTSKKDDN ILSGRTENNR VVNFKGDKSL
430 440
IGQFAMVKIT ESLPNSLRGE LI