Q0B0P6

PR
Gene name
panB
Protein name
3-methyl-2-oxobutanoate hydroxymethyltransferase
Names
Ketopantoate hydroxymethyltransferase, KPHMT
Species
Syntrophomonas wolfei subsp wolfei (strain DSM 2245B / Goettingen)
KEGG Pathway
swo:Swol_0101
EC number
2.1.2.11: Hydroxymethyl-, formyl- and related transferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-42 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0B0P6

Entry ID Method Resolution Chain Position Source
AF-Q0B0P6-F1 Predicted AlphaFoldDB

No variants for Q0B0P6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0B0P6

No associated diseases with Q0B0P6

No regional properties for Q0B0P6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q0B0P6

Functions

Description
EC Number 2.1.2.11 Hydroxymethyl-, formyl- and related transferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
3-methyl-2-oxobutanoate hydroxymethyltransferase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
pantothenate biosynthetic process The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARVTVSVLK DKKKRKEKIS MLTAYDYSLA GMVDEAGIDM ILVGDSLGNV VLGYDNTLAV
70 80 90 100 110 120
TMDDMIHHSK TVVRASKNAM VVGDMPFLSY HISKKEAVRN AGRFIQEAGC SAVKLEGGSE
130 140 150 160 170 180
RVDTVKAILD AQIPVMGHIG LTPQSVHQFG GFKVQGKDLE TAKKLVEDAR ALDQAGVYCI
190 200 210 220 230 240
VLECVPSELA RRVTEEISVP TIGIGAGPYC DGQVLVINDM LGMFRGFTPK FVRKFANLEP
250 260 270
LIMEALKNYK AEVEAGTFPA EEHCFTIKEE VLDRLY