Q0AYI8

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Syntrophomonas wolfei subsp wolfei (strain DSM 2245B / Goettingen)
KEGG Pathway
swo:Swol_0900
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

36-311 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0AYI8

Entry ID Method Resolution Chain Position Source
AF-Q0AYI8-F1 Predicted AlphaFoldDB

No variants for Q0AYI8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0AYI8

No associated diseases with Q0AYI8

6 regional properties for Q0AYI8

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 383 - 556 IPR000795
domain Small GTP-binding protein domain 386 - 542 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 44 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 310 - 355 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 657 - 772 IPR023115
domain Translation initiation factor IF-2, domain II 559 - 650 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKIRVHELA KELGIASKEM VEVLVELGLD VKNHMSTIED SQASWVKKRL SKSDEDSKKQ
70 80 90 100 110 120
PAQPVTRDEA VKKHSGEPAT QTTQKKPDNP RHVSGPRPQE GSKPSGSTGR REFSENREQS
130 140 150 160 170 180
RKGEERHSAN PRPGTQMKSP RNNAPRPTTR PENRSAGATG RTDNRAPGAA GRTDNRAPGA
190 200 210 220 230 240
VGRTDNRGAG SASRPDNRVT RPAAGRPDNK GSRPSDAKRP PQRTVPGNTP RPVSSPERTT
250 260 270 280 290 300
EKKPGEASRT LPGGAKTAGD KKAFRKNTPA FGQYQSKDYS RPGRKSKHKR KKENIEFQTP
310 320 330 340 350 360
ENIKIEGSIM VRDLAEKLNK NPAEIMKKLM ELGIMATINQ NIDFETAEIV SSLYDVKVER
370 380 390 400 410 420
ELSEEEKILE ELVDIDDDAE LIARPPVVTI MGHVDHGKTS LLDRIRQANV VSGEAGGITQ
430 440 450 460 470 480
HIGAYQVTIK NNKITFIDTP GHEAFTAMRA RGANLTDIVI LVVAADDGVM PQTVEAINHI
490 500 510 520 530 540
RAAKVPFLVA INKIDKPQAD PERIKQQLTE YNIVPEEWGG DTIFVPVSAK SGEGIENLLE
550 560 570 580 590 600
MILLVAEMNE IRANPDRAAY GLVVEGELDK GRGAVATVLV LNGTLNIGDY IICGTNWCRV
610 620 630 640 650 660
RAMIDDRGKR VDKALPSMPV EIMGWSGVPE AGGKVQVCDE KVAKEIIGLR LSEKKIEEQK
670 680 690 700 710 720
QSSRVSLDEF FQQMKDAEVK ELTLIIKGDV QGSVEALRQS LLRLATNEVK VNVIHSAVGA
730 740 750 760 770 780
ITETDVMLAS ASNAIIIGFN VRPDSKARKY AEDEKIDVRM YRVIYEAIDD VKKAMSGLLD
790 800 810 820 830 840
PEYKEKFLGR AEVRALFKVP HVGVIAGSYV IDGKIQRNAS VRVLRDGVIV YEGQLSSLKR
850 860 870 880
FKDDAKEVVE NYECGIGIKD FNDVKEGDII EAYTLEEIPR EL