Q0ANP4
Gene name |
rpoC |
Protein name |
DNA-directed RNA polymerase subunit beta' |
Names |
RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta' |
Species |
Maricaulis maris (strain MCS10) |
KEGG Pathway |
mmr:Mmar10_1801 |
EC number |
2.7.7.6: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q0ANP4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q0ANP4-F1 | Predicted | AlphaFoldDB |
No variants for Q0ANP4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q0ANP4 | |||||
No associated diseases with Q0ANP4
6 regional properties for Q0ANP4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RNA polymerase, alpha subunit | 346 - 487 | IPR000722 |
| domain | RNA polymerase, N-terminal | 237 - 516 | IPR006592 |
| domain | RNA polymerase Rpb1, domain 3 | 491 - 644 | IPR007066 |
| domain | RNA polymerase Rpb1, domain 1 | 18 - 344 | IPR007080 |
| domain | RNA polymerase Rpb1, domain 5 | 762 - 1309 | IPR007081 |
| domain | RNA polymerase Rpb1, domain 4 | 673 - 759 | IPR007083 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.6 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| DNA-directed RNA polymerase complex | A protein complex that possesses DNA-directed RNA polymerase activity. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-directed 5'-3' RNA polymerase activity | Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated transcription | The synthesis of an RNA transcript from a DNA template. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNHDVMNIFN | PAAEGPSFDR | IRIALASPEK | IHSWSFGEVK | KPETINYRTF | KPERDGLFCA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RIFGPVKDYE | CLCGKYKRIK | YKGIVCEKCG | VEVTLARVRR | ERMGHIELAA | PVAHIWFLKS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LPSRIAMILD | MALKDVERVL | YFENYVVIEP | GLTPLQPFQL | LSEEEYMEAQ | DEYGEDAFTA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GIGAEAVREI | LINMDLEAEC | AKVREDMKET | GSELKLKKYA | KRLKLMENFL | TSGNRPEWMI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MTVIPVIPPE | LRPLVPLDGG | RFATSDLNDL | YRRVINRNNR | LKRLIELRAP | DIIIRNEKRM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LQESVDALFD | NGRRGRVITG | ANKRPLKSLS | DMLKGKQGRF | RQNLLGKRVD | YSGRSVIVVG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PDLKLHECGL | PKKMALELFK | PFIYARLDAK | GLSGTVKQSK | KLVEKERPEV | WDVLDEVIRE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| HPVMLNRAPT | LHRLGIQAFE | PKLIEGKAIQ | LHPLVCAAFN | ADFDGDQMAV | HVPLSLEAQL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EARTLMMSTN | NILSPANGKP | IIVPSQDIVL | GLYYLSIEKD | NEPGEGMAFG | SRAELEAALE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SDVITLHTKI | KARWEGIDVD | GNKITKVIET | TPGRKMLVDL | LPKHAKMQPE | MIGELLTKKA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| IGALIDQVYR | HCGQKATVIF | CDQIMGLGFK | EAAKAGISFG | KDDMLIPDAK | ADLVGATRDM |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VSDYEQQYVD | GLITKGEKYN | KVVDAWAKCT | DNVADAMMDE | ISKTSVGEDG | RTSEVNSVYM |
| 730 | 740 | 750 | 760 | 770 | 780 |
| MAHSGARGSK | NQMKQLAGMR | GLMAKPSGEI | IETPIISNFK | EGLTVLEYFN | STHGARKGLA |
| 790 | 800 | 810 | 820 | 830 | 840 |
| DTALKTANSG | YLTRRLVDVA | QDCIITEEDC | GTSEGFEIQA | VVDGGDVVVS | LEQRILGRTL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| AAEVKDPASG | EVICPADTYV | DEDLAMAIEM | AGVQSVIARS | PLTCETRVGV | CATCYGRDLA |
| 910 | 920 | 930 | 940 | 950 | 960 |
| RGTRVNIGEA | VGVIAAQSIG | EPGTQLTMRT | FHIGGTAQVS | EQSFIEAGSE | GKVTFKNPST |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| VTNSDGDLIA | LSRNMQLVIV | DTEGKERESY | KLGYGTKLKV | KEGDKTTRGQ | RLGEWDPYTA |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| PVVSEVGGKV | KFVDIAEGVS | VKEETDEATG | IASKVVIDWR | GSAKANALQP | TIVVQDENGE |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| PIKLSSGSTA | SYMLAVGAIL | SVADGDTVRP | GDIVARIPTE | GAKTRDITGG | LPRVAELFEA |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| RRPKDHAVIA | EITGRVEFGR | DYKNKRRIAI | VPEGDEAEKV | EYLVPKGKHL | TCQEGDVIQK |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| GEYLLDGHPA | PHDILAILGV | PALANYLIDE | IQEVYRLQGV | PINDKHIETI | VRQMLQKIEV |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| KDPGESTYLA | AEQVDKIEFI | ETNERLEAEG | KRMATGDPVL | LGITKASLQT | RSFISAASFQ |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| ETTRVLTEAA | VQGKEDTLEG | LKENVIVGRL | IPAGTGAIMR | QYQVIADDLD | ADMLAEREAA |
| 1390 | 1400 | ||||
| VEAEGLPTEI | AEAAAEEMAA | EEGAS |