Q0AME1

PR
Gene name
ubiG
Protein name
Ubiquinone biosynthesis O-methyltransferase
Names
2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase
Species
Maricaulis maris (strain MCS10)
KEGG Pathway
mmr:Mmar10_2260
EC number
2.1.1.64: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-44 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q0AME1

Entry ID Method Resolution Chain Position Source
AF-Q0AME1-F1 Predicted AlphaFoldDB

No variants for Q0AME1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q0AME1

No associated diseases with Q0AME1

2 regional properties for Q0AME1

Type Name Position InterPro Accession
conserved_site UbiE/COQ5 methyltransferase, conserved site 33 - 48 IPR023576-1
conserved_site UbiE/COQ5 methyltransferase, conserved site 159 - 173 IPR023576-2

Functions

Description
EC Number 2.1.1.64 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
2-polyprenyl-6-hydroxyphenol methylase activity Catalysis of the reaction: S-adenosyl-L-methionine + a 3-(all-trans-polyrenyl)benzene-1,2-diol <=> S-adenosyl-L-homocysteine + H+ + a 2-methoxy-6-(all-trans-polyprenyl)phenol.
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
3-demethylubiquinone-9 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.

2 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.
ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSAAAPNTL NRPSIDPEEV EKFSRIAAEW WDPDSKFKPL HKFNPIRLGF MRDTICDHFG
70 80 90 100 110 120
LSGERPFEGL RILDIGCGGG LVCEPMARLG AHVTGVDAAE ANIKTASVHA DEQGLEIDYR
130 140 150 160 170 180
HGVAEQLIEQ DEAPFDVVLN LEVMEHVANP HTFLVDCARL VKPGGLMICA TINRTSKAFA
190 200 210 220 230 240
LAIVGAEWVM GWLPRGTHRF HKLVKPSQIR TALREGGMSL RAPVGVSYNP LTDQFSLGED
250
TAVNYMMVAE KPAG