Q09812

PR
Gene name
atg22 (SPAC2G11.13)
Protein name
Autophagy-related protein 22
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC2G11.13
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

154-259 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q09812

Entry ID Method Resolution Chain Position Source
AF-Q09812-F1 Predicted AlphaFoldDB

7 variants for Q09812

Variant ID(s) Position Change Description Diseaes Association Provenance
I_836767_G_A 129 G>S No Jeffares_SNPs
I_836770_A_G 130 I>V No Jeffares_SNPs
I_836950_G_A 190 D>N No Jeffares_SNPs
I_836970_A_G 196 I>M No Jeffares_SNPs
I_837193_T_A 271 L>M No Jeffares_SNPs
I_837935_A_G 518 H>R No Jeffares_SNPs
I_837961_T_C 527 S>P No Jeffares_SNPs

No associated diseases with Q09812

No regional properties for Q09812

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q09812

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
fungal-type vacuole membrane The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
integral component of fungal-type vacuolar membrane The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
L-amino acid efflux transmembrane transporter activity Enables the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.
L-amino acid transmembrane transporter activity Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.

3 GO annotations of biological process

Name Definition
amino acid transmembrane export from vacuole The directed movement of amino acids out of the vacuole, across the vacuolar membrane.
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
L-alpha-amino acid transmembrane transport The directed movement of L-alpha-amino acid across a membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNSPIQLHKK FSTTVWHVLS WILYAVGAGP TAIISMGVYV PLIVMKNAHD HGFLRTDHTI
70 80 90 100 110 120
PCSLYPEEPC SLNIVGPLWI DVSSIVFAAS AISTFLQMAM MVSLGVICDY GNNRRYILFS
130 140 150 160 170 180
CVIIGSISGI ILSWSPSSFL LGKIVFLILV DLNFIISQSC YDSFLPIFLR FYPITRGPIT
190 200 210 220 230 240
LESALQDETD DLDSYITNTT IDSSEEEPYL LEHSLILNES APPADVEDEH KAKIAARLSS
250 260 270 280 290 300
VGFGSFFGAA ILFQIIFTPI LYKTNNNPII LPITVTVCSC WWLILSTPLC TIVTLPVENH
310 320 330 340 350 360
SSDAILTLLY NSVKESYHSF KHAMSISSIR LFLFSRLFIN CGIQTSLSSA VIFGKARLNL
370 380 390 400 410 420
SNFQLTLLGM GISSFALLGT VIIPYLTEYF QLNSLQVVMI ISILLPMAPL YGLLGYIPGF
430 440 450 460 470 480
ENAGIRTSAD VFRATLFFGF FLGGAHSYCR SVYAQLVPSG KETRFFALYA LISQTGVLFS
490 500 510 520
HISLTLISNY TSDLRAVYIF VIVVMTLPLS SLWIMYQHSK TPNLHRSSS