Q09809

PR
Gene name
SPAC2G11.09
Protein name
Calcium permeable stress-gated cation channel 1
Names
SpCSC1
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC2G11.09
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

288-359 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q09809

Entry ID Method Resolution Chain Position Source
AF-Q09809-F1 Predicted AlphaFoldDB

4 variants for Q09809

Variant ID(s) Position Change Description Diseaes Association Provenance
I_823742_G_T 2 A>S No Jeffares_SNPs
I_824169_G_A 108 A>T No Jeffares_SNPs
I_825294_G_T 483 D>Y No Jeffares_SNPs
I_825414_C_T 523 R>C No Jeffares_SNPs

No associated diseases with Q09809

3 regional properties for Q09809

Type Name Position InterPro Accession
domain CSC1/OSCA1-like, 7TM region 441 - 708 IPR003864
domain CSC1/OSCA1-like, cytosolic domain 235 - 428 IPR027815
domain CSC1/OSCA1-like, N-terminal transmembrane domain 21 - 214 IPR032880

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
fungal-type vacuole membrane The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
calcium activated cation channel activity Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.
calcium ion transmembrane transporter activity Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.
nucleic acid binding Binding to a nucleic acid.

1 GO annotations of biological process

Name Definition
calcium ion transmembrane transport A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFNGYGIFD SDPRKNPSSD LRTQFWLAFL LGASACVFFC FFRKRWKVLY APRTTIEGLN
70 80 90 100 110 120
LPTLSSSYYK WLMDLVNIPD DVVQNCAGLD GYVFLLFFKM GIKFLSFASL LGVLIIMPVN
130 140 150 160 170 180
KHFRGDAFGN ITLSMPAKSE YFFSSPLVKK SIVQSPIIAN GSELNVGVLG PSLFNPIGNL
190 200 210 220 230 240
SDIPGLPQPG DGFLYLYVLF TYFISIFLLY VLFSSTKSIA DIRQSYLARQ NRLTDRTVFI
250 260 270 280 290 300
SGLPNELCST ENLKAYFDKL DVGSIDSLSI CRNYSYMDIL LSKKSKYVKK LEKYWSIYLS
310 320 330 340 350 360
NCKKLGISTL PPSNYLSPNR AELESTPEQL LEVPWQHHQC HPLIKTHFFG IFGQKIDAID
370 380 390 400 410 420
FYSAKLYKIS QQIENARSFD YPTTGQAFIT FESMATAQIV AQTHIDSKSL MGLHIELAPA
430 440 450 460 470 480
ANDIQWHNTY IGRWHKFFQG WFITLVTFMI ILLWTVPVGA IAVFINLDTI RRLWPELGRM
490 500 510 520 530 540
IEDLPFLNSL LRTFLPTLVY SLFISISPFL FRWLSSMQGL SSRAEEEIYA VGKNYAYLFV
550 560 570 580 590 600
NFFLVYVIAG STSIWELAKD TTSFAHFLAN RLPHQAQFFI DLIVLQGIGM FPLKLIQLGK
610 620 630 640 650 660
LSSYFVRRSF VPYSIASKKF ETPDSFSVGI FLPQPMFIML ICLCYSIISP LILVFGLIYF
670 680 690 700 710 720
IIGFLVYKYE LIYQMEHPQH STGELWSTIF LRMIFGCVIM QLTMMGLMSL RKAYWLSTVI
730 740 750 760 770 780
FPLLCFTVIS AYNFSTMIRS SMQFVSLYYI RTHQSNTLSS ESESRNSESS GSYVHPGFDL
790
SNEELPLIDL NTA