Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q09575
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q09575-F1 | Predicted | AlphaFoldDB |
No variants for Q09575
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q09575 | |||||
No associated diseases with Q09575
5 regional properties for Q09575
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Reverse transcriptase domain | 465 - 644 | IPR000477 |
| domain | Integrase, catalytic core | 844 - 997 | IPR001584 |
| domain | Zinc finger, CCHC-type | 240 - 256 | IPR001878 |
| domain | K02A2.6-like peptidase catalytic domain | 291 - 380 | IPR034128 |
| domain | Integrase zinc-binding domain | 778 - 831 | IPR041588 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| DNA polymerase complex | A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-directed DNA polymerase activity | Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group. |
| enzyme binding | Binding to an enzyme, a protein with catalytic activity. |
| nucleic acid binding | Binding to a nucleic acid. |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA integration | The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNDLKRSIQK | FQFNVAEPEA | FKRWLARNKL | TFVEDGKNLS | ERERTRLLLG | CLEESTFHRY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EDSQREISDI | YSISFDDTVT | ALTKIFGSTK | SLMMRRQQCL | QICRANGLSQ | DYLDYTNSIS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DAVLDSKLSS | MTSDEWSIFL | FLRGLNSPGD | EKAKLYLMQY | VEASEKKNEK | LKLSDVHDEW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MKFIQMHQQS | KIVSVKPSKS | SQQVDVNKVD | TNRSKKKKKP | IPRKPEKSSQ | DSKKKGEIPT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| CFYCNKKGHY | ATNCRSNPKT | GNQGGNKGKS | KGCDSVHVDG | LDVKTEHQAK | HRMSVEVCGK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DVAFQLDTGS | MITLISVKCW | EKLGSPPLEK | VPHRISCANG | TPMAVKGRCL | VKFKLKGIEY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TEYVYVRDRQ | TNLLGTSWLN | LCPQMRSALA | QIVNQVSTSE | TEASRLEVML | KNDFPEVFKD |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GLGLCTKEKA | EFRTEENAVP | VFKRARPVPY | GSLEAVETEL | NRLQEMGVIV | PITYAKWAAP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IVVIKKKGTG | KIRVCADFKC | SGLNAALKDE | FHPLPTSEDI | FSRLKGTVYS | QIDLKDAYLQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VELDEEAQKL | AVINTHRGIF | KYLRMTFGLK | PAPASFQKIM | DKMVSGLTGV | AVYWDDIIIS |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ASSIEEHEKI | LRELFERFKE | YGFRVSAEKC | AFAQKQVTFL | GFVDEHGRRP | DSKKTEAIRS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| MKAPTDQKQL | ASFLGAADWL | SRMMQDHQQN | ADDVVIAEIY | DDDDDEDDSI | IQKLNPVTET |
| 730 | 740 | 750 | 760 | 770 | 780 |
| DIRFESQKDH | EVSSVVKLVR | NDSWKPKPST | EIEKHWIRYR | DRLKLIHGCL | LLDDRVIVPK |
| 790 | 800 | 810 | 820 | 830 | 840 |
| SLQKIVLKQL | HEGHPGIVQM | KQKARSFVFW | RGLDSDIENM | VRHCNNCQEN | SKMPRVVPLN |
| 850 | 860 | 870 | 880 | 890 | 900 |
| PWPVPEAPWK | RIHIDFAGPL | NGCYLLVVVD | AKTKYAEVKL | TRSISAVTTI | DLLEEIFSIH |
| 910 | 920 | 930 | 940 | 950 | 960 |
| GYPETIISDN | GTQLTSHLFA | QMCQSHGIEH | KTSAVYYPRS | NGAAERFVDT | LKRGIAKIKG |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| EGSVNQQILN | KFLISYRNTP | HSALNGSTPA | ECHFGRKIRT | TMSLLMPTDR | VLKVPKLTQY |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| QQNMKHHYEL | RNGARAKAFQ | VNQKVYVQVH | HGNKSQWKHG | VIRRKFGGVL | YEVQVGDRMQ |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| KSHVNQIRTR | YGDYSRSSVN | PRLSSDPLGF | VGESGGDEMS | RNDDPVVTSN | GSSTDVNRGS |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| RITSELKKKE | SNAVRGQPCG | SCSPTNNDVS | APGYASRSHP | TTDPSHSVRR | SSRIRRVLDR |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| YGSSVEHPST | STGTPRGSTS | TQLGQASTRN | GSRYTASGRN | PSCQGNRYSS | IRGEGVTARR |
| ERVRTTWR |