Q09449

PR
Gene name
C05C10.2
Protein name
Uncharacterized ATP-dependent helicase C05C10.2
Names
Species
Caenorhabditis elegans
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1459-1538 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q09449

Entry ID Method Resolution Chain Position Source
AF-Q09449-F1 Predicted AlphaFoldDB

No variants for Q09449

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q09449

No associated diseases with Q09449

2 regional properties for Q09449

Type Name Position InterPro Accession
domain DNA2/NAM7 helicase-like, C-terminal 1233 - 1415 IPR041679
domain Upf1-like, C-terminal helicase domain 1253 - 1433 IPR047187

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
P granule A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
post-transcriptional gene silencing by RNA A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLPTSSNNEE NRKPENSFPP THFDTWERLS DYQKPSSSTT DDAYGKPVAK ISPTASIDER
70 80 90 100 110 120
ETGIIGSTLR QDSTDSDSTG SSNMNPYDRL DKEVISKKNA HTNSYRNDVD ELEGSLRTLG
130 140 150 160 170 180
LQKVNAPTIS SFSAWKSQSS ALPAPSSSET SKIVKAEIKA PQQPMSLNPN YFDVMREMEK
190 200 210 220 230 240
SMNIFTKLFR GSQIRNKNDL PSGRHLVNYR QNHAFDFAAM SHIWKENKME NLPKLPHRAN
250 260 270 280 290 300
LVMTLPSSRV RNSKICAFYR VLEKKEDKYI LVACHVNIHG FHRGDLRFVE VNNRTVLKGF
310 320 330 340 350 360
ERSSVIGHLF LGDILTVTEL TRCNETVSNV ASSVEDASPD APCQWMASKV VLFPRHEPVN
370 380 390 400 410 420
VQFKFTCNGM ASVVSTNEPM SVILNNLTEA KTNVEYTGIA FKSASYTVHT EDYTKKWYER
430 440 450 460 470 480
IQEEISNIMI YPKALSTIYQ YEEYTPNFVV EKQEQEEHPY QQDLEDLDLY RQHEMQTNVF
490 500 510 520 530 540
TKFFDIGKSE KRKFGPGKSI SNCRHSDAID FAAMSYIWKN IRQQHLPKLP KLPNMVLPLP
550 560 570 580 590 600
TSMPLDSEIC AFYRVLVENK SKYILIACHM NVHGYHRGDL RFLEINESTK LYGFEGRSVI
610 620 630 640 650 660
GQLFLGDIVA VTELARCNGH GSDAFKIPFD VSMSSQNTCT WMASKITLPS RPPPASVLFS
670 680 690 700 710 720
FMKNRMAVVK GCDEPMNVEV KSIQNVEPDL IYKGTAFKPE KPELNFTEGF IKKKRHQIGS
730 740 750 760 770 780
ITLRIASYPN SFGTIYNFQE SDIDNEHYKI GINAFSEEKF TEISLDEREK IVETCSLMGF
790 800 810 820 830 840
SAANTIFNGR FDCRAFKMEE IKKNGMTVMF CIENPTSQPT LGLWCAGNRI VIGGPNGDVN
850 860 870 880 890 900
GAIETVIDDP DIGYLRIAAR LSRDIPKKFS FKGDGEFFVS QREVFENEIL DDGYFKTLDP
910 920 930 940 950 960
GCNGRRIIET LYGGKPLERV VVDKRDSSIE RMMSQLFGVG SGISEHKTSG KKSEDTPTQF
970 980 990 1000 1010 1020
YFPSTPEPLA LNKYQCEYVQ MLLDGNPLII GSSPFGCGKS MTIITAALEL YKLKKNRKQL
1030 1040 1050 1060 1070 1080
LITQSNYASV NLIDIAQRVC LSGDDDLKDL KFVRFVSEKN WNELPSNCRT DSDMPYLMNK
1090 1100 1110 1120 1130 1140
LFKDWAMGRI DLTNLTCLKT HHYVQMVSHI IKNDLVNPML FGDHIAQIYD KLSADFSRAP
1150 1160 1170 1180 1190 1200
HAQTLVEAFF MIYKPDLVMV TADSAKGLLN ILRDVCAVQI DEASQLAECT LLGLLKSFNN
1210 1220 1230 1240 1250 1260
ASFGLIGDIH QLPPYCEEGL EGKLKDFGIG NTMERAIKEK MFPVCTLRNV YRCHPKTTEL
1270 1280 1290 1300 1310 1320
LSELFYDGAL VSGVSELARS DFMTKRDDFW PNPKFPMMFV NNTGASTKMG TSTSNSSEKS
1330 1340 1350 1360 1370 1380
IVGEIVQNLI NDPRNPVNPS DIGVISFYSA QTSILTEHLR GSGVKCGTVD AFQGSEKEII
1390 1400 1410 1420 1430 1440
IMCSTNERIS DFMQLSNRLN VAMSRAKQVT IIIGHLDGLR RANYWSTIVN KIEQNGNLVN
1450 1460 1470 1480 1490 1500
ANDWYQNQRR NKVSLSSYPL ISTSRQSKQQ RANEYNSQHK HVKRQSNNDY GSQRSVTNSL
1510 1520
NPEFVGKWDD ETYGDWPTIQ KST