Q08818

PR
Gene name
MSC6 (YOR354C)
Protein name
Meiotic sister-chromatid recombination protein 6, mitochondrial
Names
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
sce:YOR354C
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-127 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q08818

Entry ID Method Resolution Chain Position Source
AF-Q08818-F1 Predicted AlphaFoldDB

15 variants for Q08818

Variant ID(s) Position Change Description Diseaes Association Provenance
s15-1003126 33 S>G No SGRP
s15-1003117 36 L>I No SGRP
s15-1003101 41 D>G No SGRP
s15-1003098 42 G>E No SGRP
s15-1003008 72 D>G No SGRP
s15-1002660 188 H>R No SGRP
s15-1002594 210 N>S No SGRP
s15-1002555 223 G>D No SGRP
s15-1002516 236 S>N No SGRP
s15-1002320 301 K>N No SGRP
s15-1002237 329 S>I No SGRP
s15-1002120 368 N>S No SGRP
s15-1001644 527 P>A No SGRP
s15-1001415 603 S>N No SGRP
s15-1001408 605 H>Q No SGRP

No associated diseases with Q08818

No regional properties for Q08818

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q08818

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.

1 GO annotations of biological process

Name Definition
reciprocal meiotic recombination The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLSHNALRAF DCSKVIISRR CLTSSTSIYQ QSSVHLQETD DGHSGNREKH VSPFERVQNL
70 80 90 100 110 120
AADLKNELKA PDSDINEVFN DFKDKIESLK QKLRNPSPME RSHLLANFSS DLLQELSYRS
130 140 150 160 170 180
KNMTLDPYQV LNTLCQYKLA RSQHFTIVLK YLLYNQSPQD VIALWVKYLE TISENPVILL
190 200 210 220 230 240
QNSSSRAHMQ NIAITTIAYL SLPENTVDIN ILYKILQIDR KMGQVLPFNM IRRMLSTEFS
250 260 270 280 290 300
SLERRDVIIK NLNTLYYQYT VQDSDHFLSQ IENAPRWIDL RDLYGQYNKL EGEKNVEIIS
310 320 330 340 350 360
KFMDKFIDLD KPDQVVTIYN QYSKVFPNST SLKDCLLRAV SHLRAKSSKE KLDRILAVWN
370 380 390 400 410 420
SVIKPGDNIK NTSYATLVNA LTDSGNFNHL KEFWEEELPK KFKKDPIVKE AFLLALCQTS
430 440 450 460 470 480
PLKYDQVKGE LAETVKTKKL FNKVLLLMLD DEKVSEEQFN TFYYNHYPSD GVLPPTLDTL
490 500 510 520 530 540
SIKMYANYKF QAEDTRPQFD LLQSVSINPT DYEKVEKITK AFISVCPTVE PIRQLYKQLG
550 560 570 580 590 600
THLNARNYAD FISAEFNKPD GTVAEAKNLF SDFLSYQKTR KRNVDNTPLN ALLLGFCDKL
610 620 630 640 650 660
YKSKHSEYVP YIEKYYNLAK DSSIRVSNLA VSKILFNLAT FARNTQQLSD KEVAFINQFM
670 680 690
RDLGTNEGFR PNPKDIQILK ECDGITVPEK LT