Q08751

PR
Gene name
tvaII
Protein name
Neopullulanase 2
Names
Alpha-amylase II, TVA II
Species
Thermoactinomyces vulgaris
KEGG Pathway
EC number
3.2.1.135: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

115-192 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

17 structures for Q08751

Entry ID Method Resolution Chain Position Source
1BVZ X-ray 260 A A/B 1-585 PDB
1G1Y X-ray 300 A A/B 1-585 PDB
1JF5 X-ray 320 A A/B 1-585 PDB
1JF6 X-ray 320 A A/B 1-585 PDB
1JI2 X-ray 230 A A/B 1-585 PDB
1JIB X-ray 330 A A/B 1-585 PDB
1JL8 X-ray 320 A A/B 1-585 PDB
1VB9 X-ray 220 A A/B 1-585 PDB
1VFM X-ray 290 A A/B 1-585 PDB
1VFO X-ray 281 A A/B 1-585 PDB
1VFU X-ray 310 A A/B 1-585 PDB
1WZK X-ray 230 A A/B 1-585 PDB
1WZL X-ray 200 A A/B 1-585 PDB
1WZM X-ray 320 A A/B 1-585 PDB
2D2O X-ray 210 A A/B 1-585 PDB
3A6O X-ray 280 A A/B 1-585 PDB
AF-Q08751-F1 Predicted AlphaFoldDB

No variants for Q08751

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q08751

No associated diseases with Q08751

1 regional properties for Q08751

Type Name Position InterPro Accession
conserved_site Aminoacyl-tRNA synthetase, class I, conserved site 38 - 48 IPR001412

Functions

Description
EC Number 3.2.1.135 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
neopullulanase activity Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose).

1 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLLEAIFHEA KGSYAYPISE TQLRVRLRAK KGDVVRCEVL YADRYASPEE ELAHALAGKA
70 80 90 100 110 120
GSDERFDYFE ALLECSTKRV KYVFLLTGPQ GEAVYFGETG FSAERSKAGV FQYAYIHRSE
130 140 150 160 170 180
VFTTPEWAKE AVIYQIFPER FANGDPSNDP PGTEQWAKDA RPRHDSFYGG DLKGVIDRLP
190 200 210 220 230 240
YLEELGVTAL YFTPIFASPS HHKYDTADYL AIDPQFGDLP TFRRLVDEAH RRGIKIILDA
250 260 270 280 290 300
VFNHAGDQFF AFRDVLQKGE QSRYKDWFFI EDFPVSKTSR TNYETFAVQV PAMPKLRTEN
310 320 330 340 350 360
PEVKEYLFDV ARFWMEQGID GWRLDVANEV DHAFWREFRR LVKSLNPDAL IVGEIWHDAS
370 380 390 400 410 420
GWLMGDQFDS VMNYLFRESV IRFFATGEIH AERFDAELTR ARMLYPEQAA QGLWNLLDSH
430 440 450 460 470 480
DTERFLTSCG GNEAKFRLAV LFQMTYLGTP LIYYGDEIGM AGATDPDCRR PMIWEEKEQN
490 500 510 520 530 540
RGLFEFYKEL IRLRHRLASL TRGNVRSWHA DKQANLYAFV RTVQDQHVGV VLNNRGEKQT
550 560 570 580
VLLQVPESGG KTWLDCLTGE EVHGKQGQLK LTLRPYQGMI LWNGR