Q08743
Gene name |
YOR292C |
Protein name |
Vacuolar membrane protein YOR292C |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YOR292C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q08743
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q08743-F1 | Predicted | AlphaFoldDB |
3 variants for Q08743
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s15-866526 | 19 | N>S | No | SGRP | |
| s15-866471 | 37 | R>S | No | SGRP | |
| s15-866098 | 162 | D>N | No | SGRP |
No associated diseases with Q08743
No regional properties for Q08743
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q08743 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| fungal-type vacuole | A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| vacuolar membrane | The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q6DIY8 | mpv17l2 | Mpv17-like protein 2 | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPLQLFGRDQ | IVVHYDNGNM | SNDDQNHQSV | LGSWTRRAAA | ALRTLMNKRI | QRITLTHWLL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LVIWVTSLWK | FTSHYRQLYA | NSAVFATLCT | NILLFGISDI | LAQSIACFYS | YHVDPIPQIL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NDTFHHVQNN | RDVENGGGYE | SDELSIFNDF | TSEHSSYTDN | DDYPELDRPL | ATFKTDTFDF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FRWGCFMFWG | FFISFFQAPW | YKFLNFFYTE | DPTVVQVFER | VLSDQLLYSP | ISLYCFFMFS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NYVMEGGDKD | TLGKKIQRLY | ISTLGCNYLV | WPMVQFINFL | IMPRDFQAPF | SSSVGVVWNC |
| FLSMRNASK |