Q08726
Gene name |
GPN2 |
Protein name |
GPN-loop GTPase 2 |
Names |
Antigenic surface determinant protein OA3, Integrin-associated protein, IAP, Protein MER6, ATP-binding domain 1 family member B homolog |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YOR262W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q08726
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q08726-F1 | Predicted | AlphaFoldDB |
2 variants for Q08726
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s15-818144 | 285 | A>V | No | SGRP | |
| s15-818147 | 286 | N>S | No | SGRP |
No associated diseases with Q08726
No regional properties for Q08726
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q08726 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| establishment of mitotic sister chromatid cohesion | The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle. |
| protein import into nucleus | The directed movement of a protein from the cytoplasm to the nucleus. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPFAQIVIGP | PGSGKSTYCN | GCSQFFNAIG | RHSQVVNMDP | ANDALPYPCA | VDIRDFITLE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EIMQEQQLGP | NGGLMYAVES | LDNSIDLFIL | QIKSLVEEEK | AYLVFDCPGQ | VELFTHHSSL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FNIFKKMEKE | LDIRFCVVNL | IDCFYMTSPS | QYISILLLAL | RSMLMMDLPH | INVFSKIDML |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KSYGELPFRL | DYYTEVQDLD | YLEPYIEKEG | SSVLGKKYSK | LTETIKELVS | DFNLVSFEVL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SVDDKESMIN | LQGVIDKANG | YIFGASEVGG | DTVWAEASRE | GALIANYDIQ | DRWIDNKEKY |
| 310 | 320 | 330 | 340 | ||
| DKEEEEKRTA | LLKEQELQNK | AVDVNEEDEW | ENALKEWEEK | QGMDFVR |