AiPD: Autoinhibited Protein Database

Gene name	NRT1 (THI71, YOR071C, YOR29-22)
Protein name	Nicotinamide riboside transporter 1
Names	Thiamine transport protein 71
Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway	sce:YOR071C
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

531-598 (Predicted disordered autoinhibitory region) PR

531-598 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q08485-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
s15-461251	10	F>I	No	SGRP
s15-461166	38	A>E	No	SGRP
s15-461016	88	T>I	No	SGRP
s15-460873	136	S>A	No	SGRP
s15-460867	138	A>S	No	SGRP
s15-460575	235	V>A	No	SGRP
s15-460516	255	I>V	No	SGRP
s15-460461	273	L>W	No	SGRP
s15-460450	277	T>A	No	SGRP
s15-460443	279	S>T	No	SGRP
s15-460441	280	V>I	No	SGRP
s15-460432	283	L>I	No	SGRP
s15-460423	286	P>T	No	SGRP
s15-460381	300	T>S	No	SGRP
s15-460326	318	Y>C	No	SGRP
s15-460039	414	I>V	No	SGRP
s15-459845	478	K>N	No	SGRP
s15-459603	559	S>T	No	SGRP
s15-459570	570	T>I	No	SGRP
s15-459565	572	S>P	No	SGRP
s15-459562	573	E>K	No	SGRP
s15-459552	576	N>T	No	SGRP

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q08485

		Description
EC Number
Subcellular Localization	Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

Name	Definition
5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transporter activity	Enables the transfer of 5-amino-1-ribofuranosylimidazole-4-carboxamide from one side of a membrane to the other.
nicotinamide riboside transmembrane transporter activity	Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.
nucleobase transmembrane transporter activity	Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.

Name	Definition
5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport	The process in which 5-amino-1-ribofuranosylimidazole-4-carboxamide is transported across a membrane.
nicotinamide riboside transport	The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
nucleobase transport	The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
thiamine transport	The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins