Q08470
Gene name |
l(2)gl (GA15420) |
Protein name |
Lethal(2) giant larvae protein |
Names |
p127 |
Species |
Drosophila pseudoobscura pseudoobscura (Fruit fly) |
KEGG Pathway |
dpo:Dpse_GA15420 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q08470
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q08470-F1 | Predicted | AlphaFoldDB |
No variants for Q08470
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q08470 | |||||
No associated diseases with Q08470
6 regional properties for Q08470
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 115 - 156 | IPR001680-1 |
| repeat | WD40 repeat | 173 - 213 | IPR001680-2 |
| repeat | WD40 repeat | 400 - 451 | IPR001680-3 |
| repeat | WD40 repeat | 497 - 537 | IPR001680-4 |
| repeat | WD40 repeat | 591 - 627 | IPR001680-5 |
| domain | Lethal giant larvae homologue 2 | 268 - 362 | IPR013577 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLKFIRGKGQ | QPTAERQRLQ | KDLFAYRKTA | QHGFPHKPSA | LAYDPVAKLM | AIGTQTGAIK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VFGQPGVELY | AQHTLVNNSA | AELNVQLLEW | VYGTGRILSL | TAANQLILWE | PVGTTLVPIK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TLPFDGKLKK | VSSLCCSLNK | DLLWIGTEGG | NIYQLDLKSF | TIREPVIYHD | VVLEQVPPTY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KLNPGAIESI | RQLPNSLNKL | LIAYNRGLCV | LWDMQTSAVE | RAYIAPGHGQ | SVGLSVNSTG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TEFSWYHADG | SYATWSIDNG | EPPQNVNYVP | YGPDPCKSIN | RLYKGQRGTN | DVIVFSGGMP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RSAYGDHNCV | SVHVSDGHKV | CLDFTSKVID | FFVTYKEGSD | DVEVLIVLLE | EELCAYDLTD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PSILSIKAPY | LHSVHASAVT | CNYLASQVTQ | GVYERILRAG | DEQDIDYSSI | DWPITGGVLT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DDSVESDEDE | VVKDYEILLT | GHEDGSVKFW | DCTGVLLKPI | YNFKTASIFG | NEHEYREDGA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ADISAEQLDE | GEPPFRKAGL | FDPYSDDPRL | AVKKIAFCPK | TGQLVVGGTA | GQIVIADFDT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| AAEDQSSLKY | NSMNLVSDRD | GFVWKGHDQL | NVRANLLEDN | AVPLTENGVN | ITGVLQVLPP |
| 610 | 620 | 630 | 640 | 650 | 660 |
| ASITCMALEA | NWGLVSGGTA | HGLVLFDFKN | FVPVFHRCTL | NPNDLTGAGE | QLSRRKSFKK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SLRESFRKLR | KGRSTRNNPT | NQVPTTLEAR | PVERQIEARC | TDDGLGSMVR | CLLFAKTYVT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| NVNITSPTLW | SATNASTVSV | FLLHLPPAQT | AATTVPPASG | NVPPQASRRI | SAQLAKEIQL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| KHRAPVVGIS | IFDQTGSPVD | QFNAGENGSP | PHRLLIASEE | QFKVFSLPQL | KPINKYKLTA |
| 850 | 860 | 870 | 880 | 890 | 900 |
| NEGARIRRIH | FGSFSCRISP | ELLQSLHSGS | PTKSVRSHGE | GDGAGNVSAT | SAAGRGDLYH |
| 910 | 920 | 930 | 940 | 950 | 960 |
| EMALICLTNM | GDIMVLSVPE | LKRQLNAAAV | RREDINGISS | LCFTNDGEAL | YMMSSSELQR |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| IALSTSKVVQ | PTGIVEVEPL | ESEDNETASL | VNDGNESDKD | GEANKELANT | ASDTQPPVAT |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| LRAKPLELNA | DRSSLHLTNG | ISNSNSPNRA | NETITSSIGD | ITVDSVRDHL | NTTTTTLCST |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| TTEETVGRLS | VLSTQTNQAT | TTVNMKDIPD | INIPNLMDLA | SKSNTTETST | SSVVIKSVIT |
| 1150 | 1160 | ||||
| SISHEKTNGE | SENVTTKTTA | HEESQF |