Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q08280

Entry ID Method Resolution Chain Position Source
AF-Q08280-F1 Predicted AlphaFoldDB

4 variants for Q08280

Variant ID(s) Position Change Description Diseaes Association Provenance
s15-66022 134 K>N No SGRP
s15-66419 267 V>L No SGRP
s15-66814 398 F>L No SGRP
s15-66855 412 T>M No SGRP

No associated diseases with Q08280

1 regional properties for Q08280

Type Name Position InterPro Accession
domain Major facilitator superfamily domain 80 - 495 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus, cis-Golgi network membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDASSVPPKV DDYGMYTTEI SHHNPIELKN LLSSSDSRRN SQDEDSLPNN TNLIKEIDWQ
70 80 90 100 110 120
GEKVKTYPLN YQTVPLVKLQ VIACLIMFVV FGMNDQTVGA LLPTLIEYYH ISRVDVSNVF
130 140 150 160 170 180
IVQLCGYVMA SLSKERLNKH FGMRGGMLLA AGLCIVFLII LATAPSSFYV CMFCGLPLGL
190 200 210 220 230 240
GIGILDSTGN VLMGSLLVHK NELMGIMHGL YGAAAMVTPP LVSYFVEWGH WSLFFLIPLF
250 260 270 280 290 300
FSIIGMIVIF PAFKFETASK YDYLCSVENK ESNNDVEEAG DNSLMESTKA SPGFFELLRN
310 320 330 340 350 360
PAIFLYSLYL FLYLGAEITT GSWFFSYLLE TKSSNKVAMS YIAASFWTGL TVGRLCLGFV
370 380 390 400 410 420
TERFFENEYK ASKAYAFLTL SSYTLFVLVG LINSSSVFYF VVLFFVVFCC GTFIGPLFPN
430 440 450 460 470 480
ASIVALQVLP KRLHVSGVGV AVAVGGCGGA AIPYLAGVIA HTVGIQYIPL LCWIMVALFT
490
LEWTLYPKFI KGHEEYF