Q07DZ7

PR
Gene name
ASZ1 (GASZ)
Protein name
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Names
Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein
Species
Ornithorhynchus anatinus (Duckbill platypus)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-77 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q07DZ7

Entry ID Method Resolution Chain Position Source
AF-Q07DZ7-F1 Predicted AlphaFoldDB

No variants for Q07DZ7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q07DZ7

No associated diseases with Q07DZ7

No regional properties for Q07DZ7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q07DZ7

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis
  • Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
pi-body A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

6 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
DNA methylation involved in gamete generation The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
gene silencing by RNA A process in which an RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
male meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
piRNA metabolic process The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
spermatogenesis The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGRLRGPAV PGGGESSDSD EDGWDIGYTE RPDKLKDSLL SEEKDEVLKR ALTTGDGSLL
70 80 90 100 110 120
EELLNSGMQV DSSFRFGWTP LMYAASIANV DLVRILLDRG ANASFSKDQH TVLMAACSAR
130 140 150 160 170 180
VPEERILKTA ELLLSRNASP NATCRKRMSP LMYAAREGHS QLVALLVGHG AEINAQDDNG
190 200 210 220 230 240
YTALAWAARH GHKTTVLKLL ELGADKTLQT QDGKTPAEIA KRNKHPELFS MLSLTLNPLH
250 260 270 280 290 300
GKFQNITKEE NICKFLITDS EKSRDHGFSS YSAFGDLEIF LHGLQLEHLT ELLKERDITL
310 320 330 340 350 360
RQLLTLRKDD FTKIGITNVR DQKKIMDAVE ELQVEEIKFE ELPEVMKLEF SGDEFLNFLL
370 380 390 400 410 420
KLSKQCGHLT TAVQDIISQF PVHSHKIVLE WGSPECFTSV CEDLVHNAQN LGEEVGKLKH
430 440 450 460 470
LIQKLHNDQK NDSCRIPPME NVSTGKKRLW KRAAVTVCGF GLLFIVCKLT FLRK