Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q07953

Entry ID Method Resolution Chain Position Source
AF-Q07953-F1 Predicted AlphaFoldDB

3 variants for Q07953

Variant ID(s) Position Change Description Diseaes Association Provenance
s12-184321 202 G>V No SGRP
s12-184312 205 T>M No SGRP
s12-184184 248 T>S No SGRP

No associated diseases with Q07953

4 regional properties for Q07953

Type Name Position InterPro Accession
conserved_site Ribosome maturation protein SBDS, conserved site 44 - 63 IPR018023
domain Ribosome maturation protein SDO1/SBDS, central domain 109 - 172 IPR018978
domain Ribosome maturation protein SDO1/SBDS, N-terminal 14 - 101 IPR019783
domain Ribosome maturation protein SDO1/SBDS, C-terminal domain 174 - 241 IPR046928

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
guanyl-nucleotide exchange factor activity Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.

1 GO annotations of biological process

Name Definition
mature ribosome assembly The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPINQPSGQI KLTNVSLVRL KKARKRFEVA CYQNKVQDYR KGIEKDLDEV LQIHQVFMNV
70 80 90 100 110 120
SKGLVANKED LQKCFGTTNV DDVIEEIMHK GEIQLSEKER QLMLNKVNNE MLTIVSAKCI
130 140 150 160 170 180
NPVSKKRYPP TMIHKALQEL KFSPVINKPA KLQALEAIKL LVSKQIIPIV RAKMKVKVAI
190 200 210 220 230 240
SEPSRQPELI EKISKLIASS PGESTKPELD PWTCTGLIDP VNYRDLMTLC DKKGTVQVLD
MAVIDNTTHN