Q07788
PR
Gene name |
COS7 (YDL248W) |
Protein name |
Protein COS7 |
Names |
|
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YDL248W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q07788
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q07788-F1 | Predicted | AlphaFoldDB |
122 variants for Q07788
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s04-1810 | 3 | E>D | No | SGRP | |
| s04-1817 | 6 | V>I | No | SGRP | |
| s04-1817 | 6 | V>L | No | SGRP | |
| s04-1820 | 7 | K>E | No | SGRP | |
| s04-1823 | 8 | D>N | No | SGRP | |
| s04-1850 | 17 | F>V | No | SGRP | |
| s04-1875 | 25 | I>T | No | SGRP | |
| s04-1889 | 30 | D>N | No | SGRP | |
| s04-1892 | 31 | L>V | No | SGRP | |
| s04-1902 | 34 | S>N | No | SGRP | |
| s04-1904 | 35 | S>G | No | SGRP | |
| s04-1905 | 35 | S>N | No | SGRP | |
| s04-1906 | 35 | S>R | No | SGRP | |
| s04-1909 | 36 | F>L | No | SGRP | |
| s04-1930 | 43 | I>M | No | SGRP | |
| s04-1932 | 44 | Y>S | No | SGRP | |
| s04-1936 | 45 | K>N | No | SGRP | |
| s04-1944 | 48 | A>V | No | SGRP | |
| s04-1946 | 49 | F>L | No | SGRP | |
| s04-1982 | 61 | V>I | No | SGRP | |
| s04-2008 | 69 | C>W | No | SGRP | |
| s04-2009 | 70 | I>V | No | SGRP | |
| s04-2018 | 73 | L>F | No | SGRP | |
| s04-2033 | 78 | L>M | No | SGRP | |
| s04-2046 | 82 | L>Q | No | SGRP | |
| s04-2046 | 82 | L>R | No | SGRP | |
| s04-2045 | 82 | L>V | No | SGRP | |
| s04-2052 | 84 | P>L | No | SGRP | |
| s04-2055 | 85 | I>T | No | SGRP | |
| s04-2054 | 85 | I>V | No | SGRP | |
| s04-2058 | 86 | F>S | No | SGRP | |
| s04-2060 | 87 | V>F | No | SGRP | |
| s04-2060 | 87 | V>L | No | SGRP | |
| s04-2064 | 88 | L>P | No | SGRP | |
| s04-2067 | 89 | V>A | No | SGRP | |
| s04-2066 | 89 | V>F | No | SGRP | |
| s04-2073 | 91 | C>F | No | SGRP | |
| s04-2072 | 91 | C>R | No | SGRP | |
| s04-2073 | 91 | C>Y | No | SGRP | |
| s04-2076 | 92 | G>A | No | SGRP | |
| s04-2076 | 92 | G>E | No | SGRP | |
| s04-2075 | 92 | G>R | No | SGRP | |
| s04-2082 | 94 | S>F | No | SGRP | |
| s04-2087 | 96 | K>E | No | SGRP | |
| s04-2112 | 104 | I>T | No | SGRP | |
| s04-2129 | 110 | I>V | No | SGRP | |
| s04-2135 | 112 | E>K | No | SGRP | |
| s04-2147 | 116 | S>C | No | SGRP | |
| s04-2151 | 117 | S>F | No | SGRP | |
| s04-2156 | 119 | P>T | No | SGRP | |
| s04-2178 | 126 | V>A | No | SGRP | |
| s04-2200 | 133 | L>F | No | SGRP | |
| s04-2228 | 143 | N>Y | No | SGRP | |
| s04-2252 | 151 | C>G | No | SGRP | |
| s04-2306 | 169 | K>E | No | SGRP | |
| s04-2346 | 182 | Y>F | No | SGRP | |
| s04-2363 | 188 | Q>E | No | SGRP | |
| s04-2364 | 188 | Q>R | No | SGRP | |
| s04-2372 | 191 | A>S | No | SGRP | |
| s04-2373 | 191 | A>V | No | SGRP | |
| s04-2379 | 193 | G>E | No | SGRP | |
| s04-2381 | 194 | F>V | No | SGRP | |
| s04-2386 | 195 | D>E | No | SGRP | |
| s04-2392 | 197 | Q>H | No | SGRP | |
| s04-2406 | 202 | I>N | No | SGRP | |
| s04-2445 | 215 | V>A | No | SGRP | |
| s04-2447 | 216 | Q>K | No | SGRP | |
| s04-2461 | 220 | D>E | No | SGRP | |
| s04-2463 | 221 | I>T | No | SGRP | |
| s04-2462 | 221 | I>V | No | SGRP | |
| s04-2467 | 222 | H>Q | No | SGRP | |
| s04-2469 | 223 | R>Q | No | SGRP | |
| s04-2477 | 226 | L>F | No | SGRP | |
| s04-2488 | 229 | F>L | No | SGRP | |
| s04-2492 | 231 | K>E | No | SGRP | |
| s04-2493 | 231 | K>R | No | SGRP | |
| s04-2514 | 238 | S>F | No | SGRP | |
| s04-2527 | 242 | W>C | No | SGRP | |
| s04-2529 | 243 | L>P | No | SGRP | |
| s04-2539 | 246 | L>F | No | SGRP | |
| s04-2550 | 250 | C>Y | No | SGRP | |
| s04-2553 | 251 | V>A | No | SGRP | |
| s04-2552 | 251 | V>M | No | SGRP | |
| s04-2559 | 253 | Q>R | No | SGRP | |
| s04-2561 | 254 | H>N | No | SGRP | |
| s04-2564 | 255 | F>V | No | SGRP | |
| s04-2565 | 255 | F>Y | No | SGRP | |
| s04-2567 | 256 | C>G | No | SGRP | |
| s04-2568 | 256 | C>Y | No | SGRP | |
| s04-2573 | 258 | A>P | No | SGRP | |
| s04-2573 | 258 | A>T | No | SGRP | |
| s04-2574 | 258 | A>V | No | SGRP | |
| s04-2578 | 259 | F>L | No | SGRP | |
| s04-2577 | 259 | F>S | No | SGRP | |
| s04-2579 | 260 | R>G | No | SGRP | |
| s04-2580 | 260 | R>H | No | SGRP | |
| s04-2582 | 261 | I>F | No | SGRP | |
| s04-2587 | 262 | L>F | No | SGRP | |
| s04-2590 | 263 | C>W | No | SGRP | |
| s04-2591 | 264 | P>T | No | SGRP | |
| s04-2595 | 265 | G>V | No | SGRP | |
| s04-2597 | 266 | L>V | No | SGRP | |
| s04-2600 | 267 | F>I | No | SGRP | |
| s04-2611 | 270 | M>I | No | SGRP | |
| s04-2609 | 270 | M>L | No | SGRP | |
| s04-2621 | 274 | L>F | No | SGRP | |
| s04-2629 | 276 | Q>H | No | SGRP | |
| s04-2628 | 276 | Q>R | No | SGRP | |
| s04-2635 | 278 | M>I | No | SGRP | |
| s04-2640 | 280 | T>M | No | SGRP | |
| s04-2643 | 281 | T>I | No | SGRP | |
| s04-2646 | 282 | A>V | No | SGRP | |
| s04-2651 | 284 | L>F | No | SGRP | |
| s04-2652 | 284 | L>P | No | SGRP | |
| s04-2685 | 295 | L>S | No | SGRP | |
| s04-2746 | 315 | M>I | No | SGRP | |
| s04-2772 | 324 | A>V | No | SGRP | |
| s04-2779 | 326 | K>N | No | SGRP | |
| s04-2778 | 326 | K>R | No | SGRP | |
| s04-2800 | 333 | D>E | No | SGRP | |
| s04-2871 | 357 | L>P | No | SGRP | |
| s04-2909 | 370 | E>K | No | SGRP |
No associated diseases with Q07788
No regional properties for Q07788
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q07788 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| fungal-type vacuole | A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| cargo receptor activity | Binding specifically to a substance (cargo) to deliver it to a transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKENEVKDEK | SVDVLSFKQL | ESQKIVLPQD | LFRSSFTWFC | YEIYKSLAFR | IWMLLWLPLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VWWKLSNNCI | YPLIVSLLVL | FLGPIFVLVI | CGLSRKRSLS | KQLIQFCKEI | TENTPSSDPH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DWEVVVANLN | SYLYENKAWN | TKNFFFNATD | CEKMFRTTVL | EPFSLKKDKA | AKVKSFKDSV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PYIEEALQVY | ATGFDKQWKL | FITEKSWSPV | GLEDVQLPKD | IHRSKLTWFL | KRIFTIYSLP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LWLAFLNCIC | VSQHFCLAFR | ILCPGLFFLM | MVWLFQNMRT | TALLVKMEHK | MQFLLTIINE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QESGANGWDE | IARKMNRYLF | EKKAWKNEEF | FFDGIDCEWF | FSHFFYRLLS | AKKSMWLLPL |
| 370 | 380 | ||||
| NVELWPYIKE | AQLSRNEESL | MKK |