Q07705

PR
Gene name
rnhA
Protein name
Ribonuclease H
Names
RNase H
Species
Mycolicibacterium smegmatis (Mycobacterium smegmatis)
KEGG Pathway
msn:LI99_27500
EC number
3.1.26.4: Endoribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

111-159 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q07705

Entry ID Method Resolution Chain Position Source
AF-Q07705-F1 Predicted AlphaFoldDB

No variants for Q07705

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q07705

No associated diseases with Q07705

1 regional properties for Q07705

Type Name Position InterPro Accession
conserved_site Ribonuclease P, conserved site 55 - 69 IPR020539

Functions

Description
EC Number 3.1.26.4 Endoribonucleases producing 5'-phosphomonoesters
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
nucleic acid binding Binding to a nucleic acid.
RNA-DNA hybrid ribonuclease activity Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.

1 GO annotations of biological process

Name Definition
RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQDPVIIHT DGGCRPNPGP GGWGAVLRHR EHVREMFGGE AAVTSNNRME LTAPIMALEA
70 80 90 100 110 120
LTRPVTVHLY TDSTYVRNGI TKWVLGWERN GWMTAAKQPV KNVDLWQRLQ AACARHQVEW
130 140 150
FWVKGHSGIG DNELADELAT RGLQEAVGLT TSSAGTSLR