Q07635
Gene name |
dpo2 (SSO1459/SSO8124) |
Protein name |
DNA polymerase 2 |
Names |
DNA polymerase B2, DNA polymerase II |
Species |
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) |
KEGG Pathway |
sso:SSO8124 |
EC number |
2.7.7.7: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q07635
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q07635-F1 | Predicted | AlphaFoldDB |
No variants for Q07635
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q07635 | |||||
No associated diseases with Q07635
1 regional properties for Q07635
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DNA-directed DNA polymerase, family B, multifunctional domain | 324 - 454 | IPR006134 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.7 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-directed DNA polymerase activity | Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group. |
| nucleotide binding | Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated DNA replication | A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGRTQPSYTM | AVNRELEKLE | RIIERLHSPI | LSLLLERVKE | KVRYTQSASY | DELVDPYNLV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YFALIWALAE | ECEKMEEYVL | DAYPIKGGVK | LFLSNFKEKT | IRTTFPVYTI | TDNPDIVLQH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEVRYYEKEK | WKTLDGKEVK | VYRFEVESLD | AYYYMRKRLN | VVNETPTVLS | QTLYRLGIKP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FRRFRSSDDE | FPKVTIARVV | PLDWYGESLK | GKVFEVKINN | EVRRFYEKPE | VEVDIAECLG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EACNYVKSNV | KIRIEKKRSP | VSAKGLIEWS | FISLTPIHEI | AYATIGKVLT | INEAWVAFKR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RIIIPKVVPR | VEKLRRLEDI | MMVDKGGLIL | FPQPGCYDNV | YQVDFSSMYP | SLIVKHNISA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ETVEACDDIK | TELHSICLKE | KGIIPEALQW | LIERKSELKK | IDEERAEAIK | WILVASFGYL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GYRNSLFGKI | EAYEMVTYLA | RKTLRRTMEI | AEEMGLRVLH | GIIDSLVVKG | DNVDKFIEKV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EKETGLRLDY | KRYNWIIFTI | TRNNTPYPTR | YIANMNGEMI | AKGLIRENMP | NIVKSFLEDV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LREFSSAKTC | SDVKKLRIRD | LFEHYRKRAI | NGEPIDYVIW | IKDVPYVRGI | KGFYEARLGY |
| 610 | 620 | ||||
| MGRDVNYYIN | YLKRVYEDVE | EVMSRC |