AiPD: Autoinhibited Protein Database

Gene name	YDL073W
Protein name	UPF0592 protein YDL073W
Names
Species	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway	sce:YDL073W
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

647-765 (Predicted disordered autoinhibitory region) PR

647-765 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q07454-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
s04-326684	24	M>I	No	SGRP
s04-327030	140	I>L	No	SGRP
s04-327052	147	S>F	No	SGRP
s04-327281	223	F>L	No	SGRP
s04-327540	310	D>N	No	SGRP
s04-327549	313	I>V	No	SGRP
s04-327597	329	T>A	No	SGRP
s04-327733	374	N>S	No	SGRP
s04-327753	381	R>G	No	SGRP
s04-328142	510	K>N	No	SGRP
s04-328153	514	S>N	No	SGRP
s04-328243	544	S>N	No	SGRP
s04-328281	557	D>N	No	SGRP
s04-328287	559	I>V	No	SGRP
s04-328630	673	P>H	No	SGRP
s04-328685	691	D>E	No	SGRP
s04-328741	710	N>T	No	SGRP
s04-328816	735	K>R	No	SGRP
s04-328918	769	I>N	No	SGRP
s04-328936	775	N>S	No	SGRP
s04-328957	782	Y>S	No	SGRP
s04-328981	790	R>K	No	SGRP
s04-328986	792	E>K	No	SGRP
s04-328992	794	I>L	No	SGRP
s04-329052	814	A>T	No	SGRP
s04-329133	841	T>A	No	SGRP
s04-329262	884	I>V	No	SGRP
s04-329319	903	A>P	No	SGRP

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q07454

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
No GO annotations for cellular component

Name	Definition
MAP-kinase scaffold activity	The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.

Name	Definition
negative regulation of MAP kinase activity	Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
osmosensory signaling pathway via Sho1 osmosensor	The series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins