Q07353

PR
Gene name
AN3
Protein name
Naringenin,2-oxoglutarate 3-dioxygenase
Names
FHT, Flavanone-3-hydroxylase, F3H
Species
Petunia hybrida (Petunia)
KEGG Pathway
EC number
1.14.11.9: With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q07353

Entry ID Method Resolution Chain Position Source
AF-Q07353-F1 Predicted AlphaFoldDB

No variants for Q07353

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q07353

No associated diseases with Q07353

2 regional properties for Q07353

Type Name Position InterPro Accession
domain NADH:ubiquinone oxidoreductase, 30kDa subunit 93 - 214 IPR001268
conserved_site NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site 174 - 195 IPR020396

Functions

Description
EC Number 1.14.11.9 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
L-ascorbic acid binding Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
metal ion binding Binding to a metal ion.
naringenin 3-dioxygenase activity Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2.

3 GO annotations of biological process

Name Definition
coumarin biosynthetic process The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.
flavonoid biosynthetic process The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
response to molecule of fungal origin Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
IPRVTPSTLT ALAEEKTLQT SFIRDEDERP KVAYNQFSNE IPIISLEGID DETGKRAEIC
70 80 90 100 110 120
DKIVKACEDW GVFQVVDHGV DAEVISQMTT FAKEFFALPP EEKLRFDMSG GKKGGFIVSS
130 140 150 160 170 180
HLQGEVVQDW REIVTYFSYP TRARDYSRWP DKPEGWIAVT QKYSEKLMEL ACKLLDVLSE
190 200 210 220 230 240
AMGLEKEALT KACVDMDQKV VVNFYPKCPE PDLTLGLKRH TDPGTITLLL QDQVGGLQAT
250 260 270 280 290 300
KDNGKTWITV QPVEGAFVVN LGDHGHFLSN GRFKNADHQA VVNSNSSRLS IATFQNPAPE
310 320 330 340 350 360
AIVYPLKIRE GEKSIMDEPI TFAEMYRRKM SKDLELARLK KQAKEQQLQA EVAAEKAKLE
SKPIEEILA