Q07346
Gene name |
GAD |
Protein name |
Glutamate decarboxylase |
Names |
GAD |
Species |
Petunia hybrida (Petunia) |
KEGG Pathway |
|
EC number |
4.1.1.15: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q07346
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1NWD | NMR | - | B/C | 470-495 | PDB |
| AF-Q07346-F1 | Predicted | AlphaFoldDB |
No variants for Q07346
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q07346 | |||||
No associated diseases with Q07346
No regional properties for Q07346
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q07346 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.15 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
| glutamate decarboxylase activity | Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2. |
| pyridoxal phosphate binding | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glutamate metabolic process | The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVLSKTVSQS | DVSIHSTFAS | RYVRTSLPRF | KMPDNSIPKE | AAYQIINDEL | MLDGNPRLNL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ASFVTTWMEP | ECDKLMMDSI | NKNYVDMDEY | PVTTELQNRC | VNMIAHLFNA | PLEDGETAVG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VGTVGSSEAI | MLAGLAFKRK | WQNKMKAQGK | PCDKPNIVTG | ANVQVCWEKF | ARYFEVELKE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VKLSEGYYVM | DPEKAVEMVD | ENTICVAAIL | GSTLNGEFED | VKRLNDLLVE | KNKETGWDTP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IHVDAASGGF | IAPFIYPELE | WDFRLPLVKS | INVSGHKYGL | VYAGIGWVVW | RNKDDLPDEL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IFHINYLGAD | QPTFTLNFSK | GSSQVIAQYY | QLIRLGYEGY | KNVMENCQEN | ASVLREGLEK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TGRFNIISKE | IGVPLVAFSL | KDNRQHNEFE | ISETLRRFGW | IVPAYTMPPN | AQHITVLRVV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IREDFSRTLA | ERLVRDIEKV | LHELDTLPAR | VNAKLAVAEE | QAAANGSEVH | KKTDSEVQLE |
| 490 | |||||
| MITAWKKFVE | EKKKKTNRVC |