Q07048

PR
Gene name
Protein name
RNA-directed RNA polymerase
Names
p104
Species
Saccharomyces 23S RNA narnavirus (ScNV-23S)
KEGG Pathway
vg:949220
EC number
2.7.7.48: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

843-933 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q07048

Entry ID Method Resolution Chain Position Source

No variants for Q07048

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q07048

No associated diseases with Q07048

2 regional properties for Q07048

Type Name Position InterPro Accession
domain Integrase, catalytic domain 155 - 332 IPR002104
domain Core-binding (CB) domain 44 - 129 IPR044068

Functions

Description
EC Number 2.7.7.48 Nucleotidyltransferases
Subcellular Localization
  • Host cytoplasm
  • The virus has no extracellular transmission pathway
  • It exists as a ribonucleoprotein viral particle in the host cytoplasm and can be transmitted through mating or cytoplasmic mixing (cytoduction)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell cytoplasm The cytoplasm of a host cell.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
RNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHHKVNVKTQ REVHFPMDLL QACGASAPRP VARVSRATDL DRRYRCVLSL PEERARSVGC
70 80 90 100 110 120
KWSSTRAALR RGLEELGSRE FRRRLRLADD CWRAICAAVC TGRKFPSFSV TDRPARARLA
130 140 150 160 170 180
KVYRMGRRLL VGVVCRGESV VSDLKQECAD LRRVIFEGST RIPSSSLWGL VGVLGWTSPE
190 200 210 220 230 240
RAMQLTFIGR ALPYGSPDVE RRALASHAAT LSIPAECHPN YLVAAEQFAK SWADDNLPRK
250 260 270 280 290 300
FRIYPIAVQE SSCMEYSRAQ GGLLQSFRKG FVGYDPAAPS ADPDDLELAK ERGFSRIRAS
310 320 330 340 350 360
WYSTFRYRGE LKSTNQSLEA RVAVVPERGF KARIVTTHSA SRVTFGHQFR RYLLQGIRRH
370 380 390 400 410 420
PALVDVIGGD HRRAVETMDG DFGLLRPDGR LLSADLTSAS DRIPHDLVKA ILRGIFSDPD
430 440 450 460 470 480
RRPPGTSLAD VFDLVLGPYH LHYPDGSEVT VRQGILMGLP TTWPLLCLIH LFWVELSDWA
490 500 510 520 530 540
PARPNHSRGF VLGESFRICG DDLIAWWRPE RIALYNQIAV DCGAQFSAGK HLESKTWGIF
550 560 570 580 590 600
TEKVFTVKPV KMKVRVRSEP SLKGYVFSRS SAFSCRMGGK GITGIRAARL YTIGAMPRWS
610 620 630 640 650 660
RRIRDVYPGS LEHRTASQRY GEPVTVYRFG RWSSAIPLRW AVRAPTRTVG NPVQSLPDWF
670 680 690 700 710 720
TVGPAASSVA ADSNAFGAVS RVLRRMFPGL PRKLASAGIP PYLPRVFGGG GLVKSTGLTT
730 740 750 760 770 780
KIGAVASRRW MSRIGHDLYR SRERKSTLGR VWTLSTSPAY AASLHEVEKF MDRPDIILTR
790 800 810 820 830 840
KCRNPMLKHA RELGLFEEVF ESRVGGGILW ASLNGKALVE SHSPSILQVS RNLRRSLACP
850 860 870 880 890 900
SGGFLRPSAP IGKLVQRHTL PRGTVWFLES SATDSARQGG MGLPPPPPPP LGGGGMAGPP
910 920 930 940
PPPFMGLRPE SSVPTSVPFT PSMFSERLAA LESLFGRPPP S