Q06975

PR
Gene name
gar1 (SPBC20F10.01, SPBC25H2.01c)
Protein name
H/ACA ribonucleoprotein complex subunit gar1
Names
snoRNP protein GAR1
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC20F10.01
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

90-194 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q06975

Entry ID Method Resolution Chain Position Source
AF-Q06975-F1 Predicted AlphaFoldDB

No variants for Q06975

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q06975

No associated diseases with Q06975

No regional properties for Q06975

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q06975

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
box H/ACA snoRNP complex A box H/ACA RNP complex that is located in the nucleolus.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
box H/ACA snoRNA binding Binding to a box H/ACA small nucleolar RNA.

2 GO annotations of biological process

Name Definition
snoRNA guided rRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.
snRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFRGGRGGG FRGGRGGSRP FTPSGPPDQV IELGLFMHDC EGEMVCQSTN VKIPYFNAPI
70 80 90 100 110 120
YLENKSQIGK IDEVFGPMNQ VYFTVKPSEG IVSSSFKVGD KVYLSGDKLI PLDRFLPKPK
130 140 150 160 170 180
TVGPKKPKGA RNGPAGRGGR GGFRGGRGGS RGGFGGNSRG GFGGGSRGGF GGGSRGGSRG
190
GFRGGSRGGF RGRF