Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q06839

Entry ID Method Resolution Chain Position Source
AF-Q06839-F1 Predicted AlphaFoldDB

16 variants for Q06839

Variant ID(s) Position Change Description Diseaes Association Provenance
s16-725568 59 N>K No SGRP
s16-725708 106 S>N No SGRP
s16-725941 184 P>S No SGRP
s16-726079 230 S>P No SGRP
s16-726356 322 G>D No SGRP
s16-726412 341 K>E No SGRP
s16-726478 363 I>V No SGRP
s16-726634 415 L>V No SGRP
s16-726650 420 T>N No SGRP
s16-726713 441 E>G No SGRP
s16-726728 446 G>D No SGRP
s16-727086 565 M>I No SGRP
s16-727097 569 V>G No SGRP
s16-727849 820 V>I No SGRP
s16-728277 962 I>M No SGRP
s16-728327 979 N>S No SGRP

No associated diseases with Q06839

3 regional properties for Q06839

Type Name Position InterPro Accession
domain Phox homology 271 - 506 IPR001683
domain Domain of unknown function DUF3818, PX-associated 564 - 916 IPR024554
domain PX-associated domain 7 - 149 IPR024555

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial membrane Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol binding Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITQDTPALN PTEEHYLKRE LLRCQLDYEI GKLNDQFALR KFGYPFSPND PTAPQPISNN
70 80 90 100 110 120
DSSPVLGGKG HFSVNYPMLS YVLQEFISTF PLLSTNLLVD EKFWQSKVQV FFEHFMSLGF
130 140 150 160 170 180
SESYDREEAS KRKKVSKKLS KVILLLFNSG VGSFQEQAYY NEDKFVLQSG QARKRSNIEK
190 200 210 220 230 240
FAMPTRENLE NLLTNESVFI NGWDVNIISV FNKNSRKCTE SVDNDKSSKS TPTSSPKSHA
250 260 270 280 290 300
IKSFASTSKW MKNAFNNTIN STINSMPESS ASLFSKLSLG VPSTKSKQSR KHHYFLIKIK
310 320 330 340 350 360
KQDDDDQDNS NEENSNLDHH AGYFYVTRTY SDFKKLSHDL KSEFPGKKCP RLPHRNKKVT
370 380 390 400 410 420
SMITKTEVLH NGQTKSAARE KIVNTFDTDL QSASESDNSS FLQTTNELSA TETVLTEKET
430 440 450 460 470 480
ETLRKNILNE IKEEDNIDED EYEEEGEGEE SDFDEYKDAS DSKINTLVGE KMRTSLRQYL
490 500 510 520 530 540
RTLCKDAEVS QSSSIRRFFL SGPNLDIKDI NPKIADDIRN RALIDVSNLE NQIRFQQMAL
550 560 570 580 590 600
EKSLKLQDSM KDFKTSLLKD EKYLMSLLVE IKDNTKVEDL SPLLQDFVEW CKIYISSMIY
610 620 630 640 650 660
QMFLGNDNSY ELYTQIRRLH KLMPYTVMGQ IMKFTNPIAI MRGMIELFMA QPFGGHSLLQ
670 680 690 700 710 720
TMFSTILTDD LKTQKVAIKE LERKIAEMDP GASVVTKCLK DFVFNNDTKD EHDTKLFTMD
730 740 750 760 770 780
AVNAESESMN MPVPLIVLMK SAAANLIPDE VVAGLIESYS SWKLQKEDTD ALNVTSEDQS
790 800 810 820 830 840
GIYFTHVKDL WQLYIKEHDK QLMRQLWQDP ELTQMLKAIV TMIYEPMVKI FKVARMDVAL
850 860 870 880 890 900
KNFEKFMSDL IRLVDDVING QLGVSTQFDV VEEIHNLVTK HQDAFFEFIH DVYLNDSEGI
910 920 930 940 950 960
FEGFITWITT IVKFLQKSKF GGPSERIDFN KLICRDDIDI DVKLLKVQVN NVLNKKIGAR
970 980 990 1000 1010 1020
KIYKKLLDLK VKQGTKQNNK HAAGILQKNW SDINSLVMPS SSGSFGLGDG DLVDLDLDTG
1030 1040 1050 1060 1070
DYDFLHKENE VELEKQYKDL LNLVVDESEI DKLRSQVFAQ ELKNYLEAQI AKK