Q06778

PR
Gene name
bla (oxa11)
Protein name
Beta-lactamase OXA-11
Names
Species
Pseudomonas aeruginosa
KEGG Pathway
ag:CAA80304
EC number
3.5.2.6: In cyclic amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

20-90 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q06778

Entry ID Method Resolution Chain Position Source
7N1M X-ray 196 A A/B 19-266 PDB
AF-Q06778-F1 Predicted AlphaFoldDB

No variants for Q06778

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q06778

No associated diseases with Q06778

2 regional properties for Q06778

Type Name Position InterPro Accession
domain Penicillin-binding protein, transpeptidase 57 - 259 IPR001460
active_site Beta-lactamase, class-D active site 65 - 75 IPR002137

Functions

Description
EC Number 3.5.2.6 In cyclic amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
beta-lactamase activity Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.
penicillin binding Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.

2 GO annotations of biological process

Name Definition
antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTFAAYVII ACLSSTALAG SITENTSWNK EFSAEAVNGV FVLCKSSSKS CATNDLARAS
70 80 90 100 110 120
KEYLPASTFK IPNAIIGLET GVIKNEHQVF KWDGKPRAMK QWERDLTLRG AIQVSAVPVF
130 140 150 160 170 180
QQIAREVGEV RMQKYLKKFS YGSQNISGGI DKFWLEDQLR ISAVNQVEFL ESLYLNKLSA
190 200 210 220 230 240
SKENQLIVKE ALVTEAAPEY LVHSKTGFSG VGTESNPGVA WWVGWVEKET EVYFFAFNMD
250 260
IDNESKLPLR KSIPTKIMES EGIIGG