Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q06068
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q06068-F1 | Predicted | AlphaFoldDB |
No variants for Q06068
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q06068 | |||||
No associated diseases with Q06068
1 regional properties for Q06068
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Heat shock protein 70, conserved site | 338 - 352 | IPR018181 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent protein folding chaperone | Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein folding | The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVVGFDVGN | LSSYIAVARG | GGIETMANEY | SDRLTPSVVS | FGEKSRTQGH | AARSQAITNY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KNTLSQFKRF | IARRFSDPSV | QKDAKVVPYK | ITQLPNGNVG | MQVQYLGETE | TFTPEQIYAM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ILTKLKSTAE | INLCRKVVDC | VISVPQYYTD | LERRGVIHAA | EIAGLNCLRV | ISDTTAVALA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YGIYKQDLPT | PEEKPRNVVF | VDCGHSSLQV | SVCAFNKGKL | KVLANASDKN | LGGRDFDWLL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AEHFAVDFQT | RYKMDVKSNQ | RAWLRLMAEC | DKTKKLMSAN | ATLISMNIEC | IMNDRDVSGK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ISRADFEALA | AELLKRVEVP | LKSVLEQTKL | KPEDIHSIEI | VGGSSRIPSI | KETIKKVFKK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ECSTTLNQDE | AVARGCALQC | AILSPTFKVR | DFTVTDLTPY | PIELEWKGTE | GEDGSMEVSS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KNHQAPFSKM | LTFYRKAPFE | LVARYADPNL | PIPERRIGRF | KINGVFPTTE | GESSKIKVKV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RVDGHGIFNV | ASASLIEKLP | VQAEDAMEDG | SPEENGPSKE | EGSGASQAEN | DAPMDQSPVQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GGAGEGEASA | DKEEQADNGS | KETSKDSKDQ | TSESSKSDKE | SKDQNSEGSK | SDNSSTETDA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KAAKKTKKTI | KTHELSITAT | TDELSITEVN | NFFEKEGKLI | AHDRLEKEKN | DAKNAVEEYV |
| 670 | 680 | 690 | 700 | 710 | 720 |
| YEMREKLCDK | FEQYISEKER | GSFSKLLEET | ENWLYEDGED | ETKSVYQTKI | NSLKKIGDPV |
| 730 | 740 | 750 | 760 | 770 | 780 |
| ENRFKENLER | PGAFEDFGKA | LVPYIKTLDL | YSNGDEKYSH | IEKEDMAKVE | KCVKEKVAWR |
| 790 | 800 | 810 | 820 | 830 | 840 |
| DSKVNAQNQK | APHQDPVVTA | AQIRSEIQSM | KFVCDPIINK | PKPKPKEEPP | KDNGPTPEEA |
| 850 | 860 | 870 | 880 | ||
| AKDGGPAPPT | TEGGEEKMDT | SDQAPTGEAS | KEGETKPDET | KPDVEMELD |