Q05766
Gene name |
cya (PM1811) |
Protein name |
Adenylate cyclase |
Names |
ATP pyrophosphate-lyase, Adenylyl cyclase |
Species |
Pasteurella multocida (strain Pm70) |
KEGG Pathway |
pmu:PM1811 |
EC number |
4.6.1.1: Phosphorus-oxygen lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q05766
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q05766-F1 | Predicted | AlphaFoldDB |
No variants for Q05766
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q05766 | |||||
No associated diseases with Q05766
3 regional properties for Q05766
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Adenylate cyclase class-I, N-terminal domain | 7 - 205 | IPR024685 |
| conserved_site | Adenylate cyclase class-I, conserved site | 246 - 257 | IPR024686-1 |
| conserved_site | Adenylate cyclase class-I, conserved site | 602 - 616 | IPR024686-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 4.6.1.1 | Phosphorus-oxygen lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| adenylate cyclase activity | Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cAMP biosynthetic process | The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNYDLFSAQK | KVEYLDKLRI | ERALSGSSGE | FQHVFQLLTL | LLHINHPNLP | GYVADAPVGI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ADFVISPYQK | QYLLTTVPSL | EANQSLLPSF | SYRSTNAILG | VYVMGSIASI | SQTPKSDLDT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WVCHRDDLST | KEKEALQRKT | HLLKNWAKQF | NIEINFYLMD | QKRFRCFRYA | EPLTAENCGS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AQYMLLLDEF | YRSAIRLAGK | PLLWLHLLIE | QEENYESEVE | RLVRTQQICL | DDWVDFGGLG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QLSANEYFGA | SLWQLYKGID | APYKSVIKIL | LLETYSSEYP | NTYLIARQFK | EELLTGKLNP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SHHFDPYLAM | LQRATRYLTK | HNELKRLGFV | RRSVYLKATE | GMCWQDPNAT | NNWRLQHLQK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LIQEWDWSDA | LIEELNQRAN | WKIKQVKKAH | NSLIKFLMLS | YRNLVAFARK | HKVNSSIMPQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DISVLTRKLY | TAFEELPGKI | TLLNPQISLN | LSEKNLLFFE | VKGSKTFKDG | WYVVNQTPSV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AGFVQKRYTE | YSESLNKLVA | WAYFNRILTA | NTDLHIISPN | VSLTTLRHFV | TDLRLSFPVT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VSSVTNEDLT | HACEIRSLIV | AVNLTVDPTK | KITQVKSRIQ | ASDLFSFGPK | EESLVGSIDI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TYRNLWNEIR | TLHFEGPNAI | LLALKVLSNK | IHRGAPSPKL | IQVFSYSHRY | RRTLSNIVTA |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LINRCISIQI | GDALPPQNNL | LRVAGKNWQF | FFEERGISLQ | EIHSNEELEA | TGFDTALQTE |
| 730 | 740 | 750 | 760 | 770 | 780 |
| VEEKESALPD | TSRTYPPEID | HFASEGFLQF | FFEDNSDGSF | NVYILDEANR | IEIYRNCDGQ |
| 790 | 800 | 810 | 820 | 830 | |
| KEKKILEINH | IYQSSGLDEN | NNPYKIVQRD | FNYPQFYQLL | LQENGVKIVP | FHSRLAMS |