Q05556
Gene name |
CYP2A11 |
Protein name |
Cytochrome P450 2A11 |
Names |
CYPIIA11, Cytochrome P450-IIA11 |
Species |
Oryctolagus cuniculus (Rabbit) |
KEGG Pathway |
ocu:100328596 |
EC number |
1.14.14.1: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q05556
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q05556-F1 | Predicted | AlphaFoldDB |
No variants for Q05556
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q05556 | |||||
No associated diseases with Q05556
1 regional properties for Q05556
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Cytochrome P450, conserved site | 432 - 441 | IPR017972 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.14.1 | With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| aromatase activity | Catalysis of the reduction of an aliphatic ring to yield an aromatic ring. |
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLASGLLLAA | LLACLTVMIL | LSVWRQRKLW | GKLPPGPTPL | PFIGNYLQLN | TEQMYDSLMK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IRDRYGPVFT | IHLGPRRIVV | LCGQEAVKEA | LVDQAEDFSG | RGEQATFDWL | FKGYGVAFST |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WERARPLRRF | AISTLRDFGV | GKRGIEERIQ | EEAGFLIEAF | RDTRGAFIDP | TFFLSRTVSN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VISSIVFGDR | FDYEDKEFLS | LLRMMLGSFQ | FTATPTGQLY | EMFYSVMKHL | PGPQQQAFKE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LEGLRDFIAK | KVERNQRTLD | PNSPRDFIDS | FLIRMQEEKK | DPKSEFHMKN | LVLTTLNLFF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AGTETVSTTM | RYGFLLLMKH | PDVEAKVHEE | IDRVIGRNRQ | PKFEDRAKMP | YTEAVIHEIQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RFTDMIPMGL | ARRVTRDTKF | RDFLLPKGTE | VFPMLGSVLK | DPKFFSKPRE | FYPQHFLDEK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GQFKKSDAFM | PFSVGKRYCL | GEGLARMELF | LFFTTIMQNF | RFRSQQAPQD | IDVSPKHVGF |
| 490 | |||||
| ATIPRTYTMS | FVPR |